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FDA Alert: Risks of Injectable Weight-Loss Drug Overdose

Taking more Ozempic than prescribed can land you in the hospital, they warn.

Leah Groth
By Leah GrothAug 02, 2024
Leah Groth
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Leah Groth has decades of experience covering all things health, wellness and fitness related.
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Leah Groth
By Leah GrothAug 02, 2024
Leah Groth
Writer, Editor, and Content Creator
Leah Groth has decades of experience covering all things health, wellness and fitness related.
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FACT CHECKED BY Christopher Roback
Nutrition & Diet

When it comes to drugs, following the recommended or prescribed dosages is crucial. While it can be tempting to take more than prescribed, it can be hazardous to your health. This week, the FDA issued an alert about Ozempic and other weight loss drugs, revealing there have been several reports of overdoses. However, instead of helping people lose more weight, taking more than recommended is resulting in some pretty serious side effects.

The FDA Has Received Several Reports of Ozempic Overdose

Asian woman lying sick in hospital.Shutterstock

In a press release, the FDA revealed that they have received reports of “adverse events, some requiring hospitalization, that may be related to overdoses due to dosing errors associated with compounded semaglutide injectable products.”

They maintain that people are doing it incorrectly. “Dosing errors have resulted from patients measuring and self-administering incorrect doses of the drug and health care providers miscalculating doses of the drug,” they continue. “The majority of the reports described patients mistakenly drawing up more than the prescribed dose from a multiple-dose vial during self-administration. In these instances, patients administered five to 20 times more than the intended dose of semaglutide.”

Many of the Patients Were Inexperienced with Self-Injections

Pen,Injection,Semaglutide,Ozempic, diabetes, medicine, medication, diet, weight, lossShutterstock

They encourage patients to talk with their healthcare provider or compounder about how to measure and administer the intended dose of compounded semaglutide.

“Many of the patients who received vials of compounded semaglutide lacked experience with self-injections, according to the adverse event reports. Unfamiliarity with withdrawing medication from a vial into a syringe coupled with confusion between different units of measurement (e.g., milliliters, milligrams, and “units”) may have contributed to dosing errors,” they say.

Providers Need to Counsel Patients

Doctor talking to patient in officeShutterstock

FDA encourages healthcare providers and compounders to provide patients with the appropriate syringe size for the intended dose and counsel patients on how to measure the intended dose using the syringe.

Additionally, health care providers should be vigilant when prescribing and administering compounded semaglutide, as there may be different concentrations available. If uncertain, health care providers should contact the compounder about calculating the correct dose of medication to prescribe or administer.

These Are the Signs of Ozempic Overdose

Young woman sitting on the bed with hard stomach pain.Shutterstock

According to the prescribing information for FDA-approved semaglutide injection, there are several adverse effects of overdose, including severe nausea, severe vomiting and severe hypoglycemia (low blood sugar levels).

“A prolonged period of observation and treatment for overdose symptoms may be necessary due to the long half-life of semaglutide of about one week,” they add.

RELATED:20 Possible Ozempic Side Effects

Compounded Versions Are Being Marketed for Weight Loss and Are “Riskier”

Pharmacy,Drugstore:,Beautiful,Asian,Pharmacist,Uses,Checkout,Counter,Computer,,DoesShutterstock

The FDA also reveals that there are compounded semaglutide products marketed for weight loss, which are riskier than the pure versions. “Compounded drugs pose a higher risk to patients than FDA-approved drugs because compounded drugs do not undergo FDA premarket review for safety, quality or effectiveness. Compounded drugs should only be used for patients whose medical needs cannot be met by an available FDA-approved drug,” they say.

Amongst the reports, the FDA reveals that some side effects were serious. “Some patients sought medical attention or required hospitalization. Adverse events included gastrointestinal effects (e.g., nausea, vomiting, abdominal pain), fainting, headache, migraine, dehydration, acute pancreatitis, and gallstones,” they say. If you read this article, don't miss these 20 Things You Need to Know About Ozempic and Weight Loss.

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Nutrition & Diet

FDA Alert: Risks of Injectable Weight-Loss Drug Overdose

An ambulance on an emergency call driving through the town center of Fairhope.
Shutterstock
Leah Groth
By Leah GrothAug 02, 2024
Leah Groth
Writer, Editor, and Content Creator
Leah Groth has decades of experience covering all things health, wellness and fitness related.
See Full Bio
Follow:
FACT CHECKED BY Christopher Roback
✓Fact-Checked

Our content is fact checked by our senior editorial staff to reflect accuracy and ensure our readers get sound information and advice to make the smartest, healthiest choices.

We adhere to structured guidelines for sourcing information and linking to other resources, including scientific studies and medical journals.

If you have any concerns about the accuracy of our content, please reach out to our editors by e-mailing editors@bodynetwork.com.

When it comes to drugs, following the recommended or prescribed dosages is crucial. While it can be tempting to take more than prescribed, it can be hazardous to your health. This week, the FDA issued an alert about Ozempic and other weight loss drugs, revealing there have been several reports of overdoses. However, instead of helping people lose more weight, taking more than recommended is resulting in some pretty serious side effects.

The FDA Has Received Several Reports of Ozempic Overdose

Asian woman lying sick in hospital.Shutterstock

In a press release, the FDA revealed that they have received reports of “adverse events, some requiring hospitalization, that may be related to overdoses due to dosing errors associated with compounded semaglutide injectable products.”

They maintain that people are doing it incorrectly. “Dosing errors have resulted from patients measuring and self-administering incorrect doses of the drug and health care providers miscalculating doses of the drug,” they continue. “The majority of the reports described patients mistakenly drawing up more than the prescribed dose from a multiple-dose vial during self-administration. In these instances, patients administered five to 20 times more than the intended dose of semaglutide.”

Many of the Patients Were Inexperienced with Self-Injections

Pen,Injection,Semaglutide,Ozempic, diabetes, medicine, medication, diet, weight, lossShutterstock

They encourage patients to talk with their healthcare provider or compounder about how to measure and administer the intended dose of compounded semaglutide.

“Many of the patients who received vials of compounded semaglutide lacked experience with self-injections, according to the adverse event reports. Unfamiliarity with withdrawing medication from a vial into a syringe coupled with confusion between different units of measurement (e.g., milliliters, milligrams, and “units”) may have contributed to dosing errors,” they say.

Providers Need to Counsel Patients

Doctor talking to patient in officeShutterstock

FDA encourages healthcare providers and compounders to provide patients with the appropriate syringe size for the intended dose and counsel patients on how to measure the intended dose using the syringe.

Additionally, health care providers should be vigilant when prescribing and administering compounded semaglutide, as there may be different concentrations available. If uncertain, health care providers should contact the compounder about calculating the correct dose of medication to prescribe or administer.

These Are the Signs of Ozempic Overdose

Young woman sitting on the bed with hard stomach pain.Shutterstock

According to the prescribing information for FDA-approved semaglutide injection, there are several adverse effects of overdose, including severe nausea, severe vomiting and severe hypoglycemia (low blood sugar levels).

“A prolonged period of observation and treatment for overdose symptoms may be necessary due to the long half-life of semaglutide of about one week,” they add.

RELATED:20 Possible Ozempic Side Effects

Compounded Versions Are Being Marketed for Weight Loss and Are “Riskier”

Pharmacy,Drugstore:,Beautiful,Asian,Pharmacist,Uses,Checkout,Counter,Computer,,DoesShutterstock

The FDA also reveals that there are compounded semaglutide products marketed for weight loss, which are riskier than the pure versions. “Compounded drugs pose a higher risk to patients than FDA-approved drugs because compounded drugs do not undergo FDA premarket review for safety, quality or effectiveness. Compounded drugs should only be used for patients whose medical needs cannot be met by an available FDA-approved drug,” they say.

Amongst the reports, the FDA reveals that some side effects were serious. “Some patients sought medical attention or required hospitalization. Adverse events included gastrointestinal effects (e.g., nausea, vomiting, abdominal pain), fainting, headache, migraine, dehydration, acute pancreatitis, and gallstones,” they say. If you read this article, don't miss these 20 Things You Need to Know About Ozempic and Weight Loss.

Nutrition & Diet

3 New Ozempic and Wegovy Side Effects

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Ferozan Mast
By Ferozan MastAug 19, 2024
Ferozan Mast
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Ferozan Mast is a science, health and wellness writer with a passion for making science and research-backed information accessible to a general audience.
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FACT CHECKED BY Christopher Roback
✓Fact-Checked

Our content is fact checked by our senior editorial staff to reflect accuracy and ensure our readers get sound information and advice to make the smartest, healthiest choices.

We adhere to structured guidelines for sourcing information and linking to other resources, including scientific studies and medical journals.

If you have any concerns about the accuracy of our content, please reach out to our editors by e-mailing editors@bodynetwork.com.

With 1 in 8 US adults having tried a GLP-1 drug like Ozempic or Mounjaro at some point and half of those currently using a prescription, approximately 15 million people are taking these drugs, according to a survey by KFF. With the popularity of these medications exploding, tracking side effects is more important than ever. New research published in JAMA shows that non-diabetics who take the drugs could experience serious and unpleasant side effects. Here’s what those side effects are, plus others to expect from taking a GLP-1 drug.

Pancreatitis

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Non-diabetic users have a roughly nine times higher chance of developing pancreatitis. “It's definitely important that we're talking about this, but I want to keep it in perspective,” Dr. Tara Narula tells TODAY. “These drugs have been around and treating diabetic patients for over ten years, and we've really known about a lot of these side effects, bowel obstruction, pancreatitis, in fact, many of them are on the labels for these drugs.”

Bowel Obstruction

Non-diabetic users have a four times higher risk of a bowel obstruction. “But the absolute risks are small, so these are rare,” Dr. Narula says. “We're talking about, for example, gastroparesis, which is this concept of slowing stomach emptying. We're talking about going from 0.3% with these non-GLP drugs to 1% with Ozempic, 0.3% to 0.8 or 0.7% with the other drugs. So these are small increases.”

RELATED:What Happens to Your Body When You Stop Taking Ozempic

Stomach Paralysis

Young woman sitting on the bed with hard stomach pain.Shutterstock

Non-diabetic users have a more than three-and-a-half times higher risk of stomach paralysis. “That's actually how this drug partially works, which is slowing the emptying of the stomach,” Dr. Narula says. “So it helps you feel fuller longer. The problem is, in some people, if it is severe, you will end up with nausea, vomiting, abdominal pain, feeling full bloating. So it's important we're raising awareness, but we want to keep it in perspective.”

No Off-Label Drugs

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Dr. Narula makes it clear no one should be trying to get these drugs without going through a medical professional. “People should not be getting this drug off the internet,” she says. “They should not be getting it without sitting down with a healthcare provider who can really talk to you about the risks and the benefits. Are you someone, for example, who has a history of bowel problems or pancreatitis? Then you probably shouldn't be taking this drug. Do the benefits outweigh? And yes, for obesity, we're talking about cardiovascular risks, cancer risks.”

Take It Slow

Montreal, CA - 16 November 2023: Ozempic semaglutide injection pens and box. Ozempic is a medication for obesityShutterstock

Dr. Narula recommends starting on a low dose and increasing if necessary. “For a lot of people, there is going to be a benefit here, but you really want to do it the right way in terms of starting these drugs. Start low; you don't increase it until four to six weeks. You monitor for side effects, and if you need to, you can lower the dose. This healthcare provider should be talking to you about non-GI risks as well.”

There Are Benefits Too

Montreal, CA - 25 November 2023: Hand holding Ozempic semaglutide injection pen. Ozempic is a medication for obesityShutterstock

Dr. Narula says 40 to 60% of my patients are talking about GLP-1 drugs. “I mean, so many of my patients struggle with obesity, and many of them want to know about other options besides bariatric surgery and meeting with a nutritionist,” she says. “They say I've tried everything, and I can't figure out a way to lose weight. And we know that with these medications, we are seeing benefits in a cardiovascular high-risk population for lowering the risk of heart attack and stroke. So there are benefits for those people. So it is important to talk to your doctor about it. It's not for everyone. It may be for you, but really have that conversation.”

RELATED: 20 Things You Need to Know About Ozempic and Weight Loss

Vision Issues

Close up portrait of an attractive man with eyeglasses. Poor young guy has eyesight problems. He is rubbing his nose and eyes because of wearinessShutterstock

Ozempic and Wegovy may also cause several other side effects, like vision issues. “It may seem strange that a drug made to help control diabetes could make your eyesight worse, but it’s something we’ve known about for a while,” says Raj K Maturi, MD. “A large clinical study suggested that there is an association between blood sugar control and worsening of diabetic retinopathy.”

Hypoglycemia

Measuring blood sugar with a blood glucose meterShutterstock

Ozempic may cause hypoglycemia in some people. “Signs and symptoms of low blood sugar may include dizziness or lightheadedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, and feeling jittery” Ozempic makers warn.

Gallbladder Issues

Woman with abdominal pain in the middle above the navel. She sits on the sofa at home.Shutterstock

Some people taking GLP-1 drugs may experience gallbladder issues. “Given the wide use of these drugs, these adverse events, although rare, must be considered by patients who are contemplating using the drugs for weight loss because the risk-benefit calculus for this group might differ from that of those who use them for diabetes,” according to research published in the Journal of the American Medical Association.

Thyroid Cancer

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Ozempic may cause thyroid cancer, but a study shows no significant risk. “Our study covers a broad group of patients and provides strong support that GLP-1 analogs are not associated with an increased risk of thyroid cancer,” Björn Pasternak, principal researcher at the Department of Medicine at Karolinska Institutet, said in a statement.

RELATED:20 Possible Ozempic Side Effects

Ozempic Face

Santiago, Chile, august 16th, 2023. Pen injection of semaglutide named “ozempic”, is a diabetes medicine to improve blood sugarShutterstock

Fast weight loss may lead to a more hollowed-out look to the face, hence the term ‘Ozempic Face’. “The term is misleading because this can be a side effect of any GLP-1 drug or any other cause of rapid weight loss,” Lisa Catanese, ELS, says via Harvard Health. “If weight is lost in a more gradual way, these changes may not be as noticeable. It's the faster pace of weight loss that occurs with GLP-1 drugs that can make facial changes more obvious.”

GI Issues

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GLP-1 drugs may cause constipation and diarrhea. “Gradual dosing while on Ozempic is crucial to mitigate the risk of severe constipation associated with higher doses,” Andrew Le, MD, tells Buoy Health. “Constipation caused by Ozempic usually subsides over time, with the median duration of constipation lasting 47 days.”

Fatigue and Headache

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Fatigue and headaches are also common side effects. “Gastrointestinal problems are the most common side effects since Wegovy can slow down people’s digestive systems,” Dr. Cecilia Low Wang, endocrinology, diabetes and metabolism expert, tells UC Health. “During clinical trials, some participants experienced nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, indigestion, dizziness, bloating and gas.”

RELATED: I Lost 10 Pounds in 30 Days With Walking and Eating Real Food

Severe Side Effects

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Dr. Low Wang says side effects can be so severe some people stop taking the drug. “About one in five people might stop because they are experiencing bad side effects,” she tells UC Health. “I encourage some patients to stay at the lower dose level for a longer period of time to see if they can tolerate it better and still get some benefit from the medication. Or if they don’t tolerate this medication, we might try a different one.” And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

Nutrition & Diet

20 Things You Need to Know About Ozempic and Weight Loss

Montreal, CA - 16 November 2023: Ozempic semaglutide injection pens and box. Ozempic is a medication for obesity
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Leah Groth
By Leah GrothMay 12, 2024
Leah Groth
Writer, Editor, and Content Creator
Leah Groth has decades of experience covering all things health, wellness and fitness related.
See Full Bio
Follow:
FACT CHECKED BY Christopher Roback
✓Fact-Checked

Our content is fact checked by our senior editorial staff to reflect accuracy and ensure our readers get sound information and advice to make the smartest, healthiest choices.

We adhere to structured guidelines for sourcing information and linking to other resources, including scientific studies and medical journals.

If you have any concerns about the accuracy of our content, please reach out to our editors by e-mailing editors@bodynetwork.com.

Are you thinking about using Ozempic or another weight loss drug? Before you schedule an appointment with an MD or telemedicine doctor, educating yourself about the drug will give you a better idea of whether or not it’s worth it. Here is everything you need to know about Ozempic—how it works and its benefits for weight loss, how much it costs, and the potential side effects.

How Ozempic Works

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How exactly do weight loss drugs help you lose weight? “Ozempic enhances the release and action of insulin throughout the body, which helps with fat loss,” explains Dr. Sue Decotiis, MD, NYC weight-loss doctor.

Ozempic Shuts Down Your Appetite, and You Feel Full Faster

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“Weight loss drugs also have a tremendous effect on satiety, shutting down appetite so the patient feels very full after eating much less food,” she explains. “Ozempic acts on receptors in the gut and brain that regulate appetite.”

It Also Resets Your Rate for Fat Burning

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Ozempic also targets the centers in the brain that resets a person’s set rate for fat, Dr. Decotiis says. “When your set rate is higher for fat, you tend to hold more weight. When people go on Ozempic it resets the amount of weight that your body wants to hold onto.”

It Improves Insulin Function

Santiago, Chile, august 16th, 2023. Pen injection of semaglutide named “ozempic”, is a diabetes medicine to improve blood sugarShutterstock

The main way Ozempic works is changing the way insulin works, explains Dr. Decotiis. “When insulin works well, you can burn fat, when it doesn’t you gain weight,” she says.

It Helps Regulate Hormones

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“It helps regulate people’s hormones that have changed due to aging, stress, etc., so that they can lose weight,” she continues. “When people age their hormones change and it’s harder for them to lose weight. Ozempic stimulate the hormones needed in the body for fat loss.”

It Can Help with Self-Esteem and Rarely Leads to Depression

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Dr. Decotiiis has seen a lot of positive effects on personality in her practice. “When people lose weight, they have better self-esteem, and they feel more confident in their own skin,” she says. “I have people who were using sedatives for anxiety or depression, and then when they took these drugs, they felt better and didn’t need them as much. My patient who had ADHD felt they had better focus and concentration. I have never had anyone who’s gone into depression or has felt worse after taking these drugs. My advice is to know who the patient is and supervise them accordingly.”

Ozempic Is Actually Only Approved for Those with Type 2 Diabetes

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According to the National Library of Medicine Ozempic is approved to control blood sugar levels in adults with type 2 diabetes when other medications do not control the sugar levels well enough.

It Can Also Help with Heart Health

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It is also used to reduce the risk of a stroke, heart attack, or death in adults who have type 2 diabetes along with heart and blood vessel disease. “It is not used to treat type 1 diabetes or diabetic ketoacidosis,” they say.

Wegovy Is Approved for Weight Loss

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“Semaglutide injection (Wegovy) is used to reduce the risk of a stroke, heart attack, or death in adults who are overweight or obese along with heart and blood vessel disease,” they say, adding that “used along with an individualized low-calorie, low-fat diet and exercise program” it can help with weight loss “in obese adults or overweight adults who may also have high blood pressure, diabetes, or high cholesterol” and in obese children 12 years of age or older.

It Comes in a Prefilled Pen

GDANSK, POLAND - MAY 2022: obese fat man preparing Semaglutide Ozempic injection control blood sugar levelsShutterstock

Semaglutide injection comes in a prefilled dosing pen injected once a week under the skin. “Use semaglutide injection on the same day each week at any time of day. You may change the day of the week that you use semaglutide as long as it has been 2 or more days (48 or more hours) since you used your last dose,” they say.

RELATED:What Happens to Your Body When You Stop Taking Ozempic

You Usually Start on a Low Dosage and Work Your Way Up

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Your doctor usually gets you started on a lower dosage, increasing it after four weeks. “Your doctor may increase your dose again after another four weeks based on your body's response to the medication,” they say.

Most Common Side Effects

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These are the most common side effects of Ozempic and Wegovy:

  • nausea
  • vomiting
  • diarrhea
  • abdominal pain
  • constipation
  • heartburn
  • burping

More Serious Side Effect

Portrait Of A Young Woman Suffering From Chest PainShutterstock

There are also some potential serious side effects:

  • ongoing pain that begins in the upper left or middle of the stomach but may spread to the back, with or without vomiting
  • rash; itching; swelling of the eyes, face, mouth, tongue, or throat; or difficulty breathing or swallowing
  • decreased urination; or swelling of legs, ankles, or feet
  • vision changes
  • fainting or dizziness
  • pain in upper stomach; yellowing of skin or eyes; fever; or clay-colored stools (in those receiving semaglutide [Wegovy] for management of weight loss)
  • rapid heartbeat
  • dizziness, light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety or irritability or mood changes, hunger, weakness, or feeling jittery

RELATED:5 Foods That Maximize Weight Loss on GLP-1 Medicines, According to Coach

How Much Does Ozempic Cost?

Montreal, CA - 16 November 2023: Ozempic semaglutide injection pens. Ozempic is a medication for obesityShutterstock

Just because your doctor prescribes Ozempic doesn’t mean insurance will cover it. The cost of Ozempic weighs heavily on whether your health insurance company believes that you qualify for the drug.

It’s Very Expensive Without Insurance

GDANSK, POLAND - MAY 2022: obese fat man preparing Semaglutide Ozempic injection control blood sugar levelsShutterstock

Ozempic is expensive if your insurance refuses to cover it. According to GoodRX, without insurance Ozempic can cost as little as $937.98 per month and as much as $1,014 per month.

How Much Does Ozempic Cost with Insurance

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How much does it cost with insurance? Novo also offers a savings card, which enables people with private or commercial insurance to pay as little as $25 for a 1-month, 2-month, or 3-month supply of Ozempic for up to 24 months. However, many people pay more than that, with most insurance companies covering around 85 percent of the cost.

How Much Profit Are the Drug Companies Making?

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According to a study published in JAMA Network Open Trusted Source, these drugs “can likely be manufactured for prices far below current prices, enabling wider access.” Researchers from Yale University, King’s College Hospital in London, and the nonprofit Doctors Without Borders concluded that if the producers were charging $0.89 to $4.73 a month and still making a profit. This is in contrast to the nearly $1,000 per month list price charged by Novo Nordisk for Ozempic in the US.

RELATED:15 Things to Know Before Getting Ozempic for Weight Loss

What Is Rebound Weight Gain?

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After you stop taking Ozempic, there is a good chance you may gain the weight back. One study found that one year after stopping the drug, participants regained two-thirds of their prior weight loss.

Ozempic Face

Cropped shot of a young female face. Green eyes with dark circles under the eyes. Bruises under the eyes are caused by fatigue, nervousness, lack of sleep, insomnia and stressShutterstock

"Ozempic face" is one of the most popularized side effects of GLP-1 drugs. It’s actually a side effect of rapidly losing weight and isn’t a direct result of the drug. Losing weight fast can cause facial aging, including a hallowed look, wrinkles, and sunken eyes, explains Harvard Health.

RELATED: 15 Travel Habits That Help You Stay Fit and Lose Weight on the Go

Loose Skin and Excess Fat

Woman body fat belly. Obese Woman with fat upset about her belly. Fat woman with tight clothing worried about weight diet lifestyle concept.Shutterstock

“Ozempic body” and “Ozempic butt” are two more trending terms to describe the sagging skin left behind as a result of rapid weight loss. After dropping weight fast, loose skin, pockets of stubborn fat, and stretch marks can be left behind. Treatments, including surgery, like liposuction and tummy tucks, and less invasive options, like CoolSculpting and EmSculpt Neo, as well as lasers, can help treat these conditions.

Nutrition & Diet

9 Key Differences Between Ozempic and Other GLP-1 Meds for Weight Loss

Valparaiso IN USA - March 21, 2024: Ozempic semaglutide injection pen and Rybelsus Semaglutide tablets close up
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Leah Groth
By Leah GrothJun 26, 2024
Leah Groth
Writer, Editor, and Content Creator
Leah Groth has decades of experience covering all things health, wellness and fitness related.
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Ozempic is the buzziest drug in the weight loss world. However, it isn’t the only GLP-1 drug people are using to lose weight fast. Before you try and get a prescription, there are a lot of things you need to know about the drug, including how it works and also how it compares to similar treatments on the market. Here are ten key differences between Ozempic and other GLP-1 meds for weight loss, according to triple-board-certified plastic surgeon Leo Lapuerta, MD, The Plastic Surgery Institute of Southeast Texas.

Ozempic Isn’t Even Approved for General Weight Loss

Montreal, CA - 16 November 2023: Ozempic semaglutide injection pens and box. Ozempic is a medication for obesityShutterstock

While Ozempic is probably the most well-known GLP-1, it isn’t technically even approved for general weight loss. “It is for the control of Type 2 diabetes,” Dr. Lapuerta reveals.

Most Weight Loss Drugs Aren’t Approved for Weight Loss

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In fact, most drugs being used for weight loss weren’t even intended for that purpose. “Most of the GLP-1 drugs like Rybelsus, Victoza, Trulicity, and Byetta are intended for the treatment of Type 2 diabetes with beneficial side effects that include weight loss,” explains Dr. Lapuerta.

RELATED:20 Possible Ozempic Side Effects

Some GLP-1s Offer Heart and Kidney Benefits

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There are other benefits to taking weight loss drugs. “Ozempic, Victoza, and Trulicity all have benefits for the heart and kidneys in addition to control of Type 2 diabetes,” says Dr. Lapuerta.

One Weight Loss Drug Is Injected Daily, Most of Them Are Weekly

Victoza Insulin group emerging from a medication for diabetes patients. studio shot on a white background in Viktoza box. Diabetes drugs.Shutterstock

Most of the GLP-1s, including Ozempic, require a weekly injection. However, “Victoza is unique because it is injected daily rather than weekly,” says Dr. Lapuerta.

One Is Available in Oral Format

Ozempic semaglutide injection pen and Rybelsus Semaglutide tablets close upShutterstock

And not all of them require a needle. “Rybelsus is the only GLP-1 that is available in oral format as all the other options are by injection only,” says Dr. Lapuerta.

RELATED:What Happens to Your Body When You Stop Taking Ozempic

Some of Them Are Approved for Weight Loss and Weight Management

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Ironically, while the most well-known of the bunch isn’t even approved for weight loss, the majority of the others are. “Wegovy, Saxenda, and Mounjaro (Tirzepatide) are GLP-1 agonists intended for weight loss and weight management rather than the treatment of Type 2 diabetes,” says Lapuerta.

Some Are More Effective Than Others

Valparaiso, IN USA - January 22, 2024: Wegovy semaglutide pens for treatment of chronic obesity, close upShutterstock

According to Dr. Lapuerta, results vary by brand. “Wegovy typically produces 2 to 3 times the percent weight loss as Saxenda,” he maintains.

Only One of Them Includes GIP

Basrah, Iraq - November 24, 2023: photo of Mounjaro Weight Loss Pen in handShutterstock

Mounjaro (Tirzepatide) has an edge over the competition. “It is the first GLP-1 to also include GIP, glucose-dependent insulinotropic polypeptide (GIP), another gut hormone agonist that provides better longer-term control of blood sugar as indicated by better reductions in Hemoglobin A1C levels,” says Dr. Lapuerta.

RELATED:20 Things to Avoid While on Ozempic

Some Medications Have Two Names

Zepbound injection pen from Eli Lilly is an injectable prescription medicine that may help adults with obesity, or with excess weight (overweight) Copenhagen, Denmark - November 9, 2023.Shutterstock

Don’t let names deceive you. “Zepbound is the FDA-approved version of Mounjaro specifically for weight loss,” says Dr. Lapuerta.

Keep Reading About Ozempic

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Keep educating yourself about Ozempic. Here are 15 things you should know before getting Ozempic for weight loss. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

Nutrition & Diet

Expert Reveals 5 Hidden Ozempic and Wegovy Mistakes to Avoid Now

Dr_Brian_Yeung1
Christopher Roback
By Christopher RobackJan 08, 2025
Christopher Roback
Professional Health, Science Editor and Writer
Christopher Roback is an experienced news journalist specializing in political, science, and crime news.
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Starting Ozempic or Wegovy can feel overwhelming, and many patients make critical mistakes that could affect their results. "These medications work differently from traditional treatments, and understanding how to use them correctly is crucial," explains Dr. Brian Yeung, ND, who specialize in metabolic health. With the rising popularity of GLP-1 medications for managing diabetes and weight loss, avoiding common pitfalls becomes even more important. Here are the five key mistakes to watch out for, along with expert guidance on how to prevent them.

Skipping or Inconsistent Dosing

"Consistency is crucial with GLP-1 medications," says Dr. Yeung in his video. According to Cleveland Clinic, each medication has a specific dosing schedule - some require weekly injections while others are daily. Missing doses can interrupt your progress and reduce the medication's effectiveness. Set reminders and establish a routine to stay on track.

RELATED: 20 Things You Need to Know About Ozempic and Weight Loss

Ignoring Diet and Hydration

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"Many patients don't realize these medications slow down digestion, which means you need to adjust your eating habits," Dr. Yeung points out. Cleveland Clinic confirms that GLP-1 agonists work by slowing stomach emptying and increasing feelings of fullness. Stay hydrated and focus on nutrient-rich foods to prevent potential deficiencies.

Not Monitoring Blood Sugar Properly

Diabetes,Blood,Sugar,Level,Lancelet,GlucometerShutterstock

"While these medications have a lower risk of causing hypoglycemia, regular monitoring is still essential," says Dr. Yeung. Cleveland Clinic experts warn that the risk increases when combining GLP-1s with other diabetes medications. Keep track of your blood sugar levels and know the signs of low blood sugar, which include shaking, sweating, and dizziness.

Dismissing Side Effects

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"Some initial digestive issues are common, but they shouldn't be severe or ongoing," Dr. Yeung advises. According to Cleveland Clinic, common side effects include nausea, vomiting, and diarrhea, particularly when starting the medication or increasing the dose. Don't ignore persistent or severe symptoms - contact your healthcare provider if side effects become concerning.

RELATED:20 Possible Ozempic Side Effects

Relying Solely on Medication

Montreal, CA - 16 November 2023: Ozempic semaglutide injection pens. Ozempic is a medication for obesityShutterstock

"The biggest mistake is thinking these medications work in isolation," Dr. Yeung emphasizes. Cleveland Clinic stresses that GLP-1 agonists are just one part of a comprehensive treatment plan. Successful management requires combining medication with lifestyle changes, proper diet, and regular exercise.

Understanding Your Medication

Packaging box of Wegovy (semaglutide) injectable prescription medication, weight-loss drug from Novo Nordisk AS. Pharmacy shop shelves in background. Copenhagen, Denmark - November 13, 2023.Shutterstock

Cleveland Clinic notes that GLP-1 medications work by mimicking a natural hormone that helps control blood sugar and appetite. Understanding this mechanism can help you use the medication more effectively and set realistic expectations for your treatment journey.

Tracking Progress Effectively

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Monitor more than just weight loss. Cleveland Clinic reports that GLP-1 medications can offer additional benefits, including improved blood pressure and better lipid profiles. Keep track of these various health markers to get a complete picture of your progress.

RELATED:What Happens to Your Body When You Stop Taking Ozempic

When to Contact Your Doctor

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Cleveland Clinic recommends maintaining regular check-ups and promptly reporting any persistent side effects or concerns about the medication's effectiveness. Don't wait until small issues become major problems. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

Fitness & Workouts

Simple Workout Plan to Build Strength at Home

Caroline Idiens carolinescircuits
Copyright carolinescircuits/Instagram
Leah Groth
By Leah GrothFeb 03, 2025
Leah Groth
Writer, Editor, and Content Creator
Leah Groth has decades of experience covering all things health, wellness and fitness related.
See Full Bio
Follow:
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Are you over 40 and trying to lose weight? Getting in shape can be overwhelming. However, it doesn’t have to be. One personal trainer maintains that all you need to do is master five simple exercises. Caroline Idiens is a fitness influencer and personal trainer with over 25 years of professional experience helping clients achieve their fitness goals. In a new post, she reveals a few key moves to help you shape up. “5 exercises you need to do at 40+ to build strength💪🏻add weights as you progress,” she writes.

Squats

The first exercise? Squats. “Squats are a brilliant compound functional move building lower body strength and engaging the core,” she says. “You can do bodyweight squats or use weights/bands. This exercise works quadriceps, glutes, hamstrings, core.”

Lunges

Woman doing walking lunges outdoors. Fitness, sport and healthy lifestyle concept.Shutterstock

Next up, another glute buster, lunges, a “functional move,” she explains. “You can do forward, reverse & lateral lunges. This exercise works glutes, hamstrings, quads. Again add weights as needed.”

Push-Ups

Strong senior man making strength workout, doing push ups on sports mat, exercising at home, copy space. Sporty elderly man training his body, leading active lifestyleShutterstock

Another exercise that offers a lot of bang for its buck? Push-ups, “a brilliant bodyweight exercise that build upper body strength & engage the core. Modify as needed (e.g incline push-ups against the wall or a chair),” she says. “This exercise works your chest, shoulders, triceps, and core.”

Rows

Crop anonymous female athlete in tight orange sportswear doing exercise with resistance band on rowing machine during workout in gym

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Rows, either with body weight or actual weights, as you progress. “Rows strengthen your back, improve your posture. Great functional move. They work the back muscles as well as engaging the arms & shoulders & core for stability,” she says.

Planks

Home training concept. Smiling senior woman doing elbow plank on yoga mat in living room. Positive mature lady doing her workout routine, exercising indoors, strengthening her core musclesShutterstock

And last but not least, planks. They are “a great exercise for building upper body & core strength,” she says. “They work your deep core muscles.”

Lift Weights

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“Strength training is vital as you age. My passion has always been strength training, and never more so than today,” Caroline previously wrote for Sheer Luxe. “Once we hit 30, our bone density and muscle mass decrease. Strength training plays a significant role in preventing this loss and we can actually build new bone by using weights. This can help reduce the risk of osteoporosis, which women are so susceptible to, especially post-menopause.”

There Are Lots of Benefits

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“Moreover, strength training gives you such a feeling of power in everyday life – it’ll help with sleep, anxiety, co-ordination and will also help you manage your weight,” she wrote, adding that it “won’t make you bulky,” despite popular misconception. “It’s a myth that using weights will make you bulky – unless you are using very heavy weights and dramatically changing your diet, this simply isn’t true. It’s also important to remember that you can’t spot reduce fat. Your body works as a whole and, whilst you can tone a particular area, working the full body consistently along with a sensible diet will make the difference.”

Science Supports Strength Training for Weight Loss

Mature athlete using rowing machine while working out in a gym.Shutterstock

According to the Mayo Clinic, strength and weight training help reduce body fat, preserve and increase lean muscle mass, and burn calories more efficiently. Strength training may also help you:

  • Develop strong bones
  • Manage your weight
  • Enhance your quality of life
  • Manage chronic conditions
  • Sharpen your thinking skills.

She Also Recommends Cardio

Portrait of active mature woman training on stationary bike workout in gymShutterstock

“In an ideal world, combine weights with cardio,” Caroline adds. Why is it important to do both? “While you may burn more calories in a cardio workout, strength training builds muscle. The two aren’t mutually exclusive and, for a leaner, fitter body, you should combine the two. Cardio is essential for heart health and for building stamina and endurance. At the same time, when we lift weights, we build muscle, boost metabolism and reduce our risk of injury,” she says.

Diet Matters

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And, you can’t out-exercise a bad diet. “People think they can exercise, eat rubbish and still see great results,” she recently told The Daily Mail. “Sadly it doesn’t work like that. It’s about balance and moderation.” As for one main meal tip? “And protein with every meal – you need it for strength training,” she says.

Here Is What She Eats in a Day

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Caroline starts her day with tea, coffee, and a banana. Then, after her 9 am workout class, she has breakfast, usually scrambled egg and avocado on sourdough. For lunc,h she likes chicken salad. Dinner might be a teriyaki salmon noodle stir-fry. As for snacks, she might have fruit and a bit of chocolate in the afternoon. She also drinks a lot of water. And if you enjoyed this article, don't missI’m a Nutritionist and Here Are 25 Weight Loss Truths You Need to Hear.

Nutrition & Diet

Top 4 Mexican Meals for Weight Loss

Brittney Blanco bylt.by.britt
Copyright bylt.by.britt/Instagram
Leah Groth
By Leah GrothFeb 03, 2025
Leah Groth
Writer, Editor, and Content Creator
Leah Groth has decades of experience covering all things health, wellness and fitness related.
See Full Bio
Follow:
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Do you want to lose weight by eating Mexican food? While ethnic cuisine might not be the first thing to come to mind if you are on a diet, according to one expert, there are a handful of south-of-the-border-inspired meals that can fuel fat-burning. Brittney Blanco is a Macros Nutrition Coach and digital creator who regularly shares her weight loss and stay-fit tricks and tips with her followers. In a new post, she reveals a few of her go-to concoctions that help her lose weight. “4 Mexican meals I eat on repeat when I’m trying to drop body fat and gain muscle,” she writes.

High-Protein Chicken Fajita Bowl

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Ingredients: 5 oz grilled chicken breast, 1/2 cup cooked white rice, 1/2 cup sautéed bell peppers & onions, 1/4 avocado (sliced), 1 tbsp salsa, 1 tbsp plain Greek yogurt (sour cream substitute)

Macros: Calories: ~450 | Protein: 45g | Carbs: 40g | Fats: 12g

Lean Turkey Taco Lettuce Wraps

Raw Turkey breast fillets minced meat on black plate ready to cookShutterstock

Ingredients: 5 oz extra-lean ground turkey (99%), 1/4 cup black beans, 1/4 cup diced tomatoes, 1 tbsp guacamole, 3 large romaine lettuce leaves (as taco shells), 1 tbsp shredded cheese (optional)

Macros: Calories: ~420 | Protein: 50g | Carbs: 25g | Fats: 12g

Carne Asada with Cilantro Lime Cauliflower Rice

Modern design barbecue dry aged wagyu bavette de flanchet steak with chili and chimichurri sauce as top view on a wooden cutting board

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Ingredients: 6 oz grilled flank steak, 1 cup cauliflower rice (sautéed with lime juice & cilantro), 1/4 avocado, 1 tbsp pico de gallo

Macros: Calories: ~480 | Protein: 55g | Carbs: 15g | Fats: 20g

Protein-Packed Huevos Rancheros

Huevos Rancheros tostadas with fried egg, tomato salsa, bean paste and cheese. Mexican food

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Ingredients: 3 egg whites + 1 whole egg, 1 small corn tortilla, 1/4 cup black beans, 2 tbsp salsa, 1 tbsp cotija cheese (optional)

Macros: Calories: ~350 | Protein: 35g | Carbs: 30g | Fats: 10g

Sweet Potato Bowl

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In a previous post she reveals meals she “eats on repeat” when she wants to lose weight fast. The first one? A sweet potato bowl, filled with fiber, protein, and healthy fat.

  • 4 oz cooked lean ground beef
  • 1 cup roasted sweet potatoes
  • 1/2 avocado
  • Tomatoes and onions
  • 550 calories, 31g protein.

Chicken Salad

Woman, diet and person eating salad in her home kitchen and is happy for a meal with nutrition or healthy lunch. Smile, food and young female vegan in her apartment or house and eat vegetablesShutterstock

Next up is Brittney’s chicken salad.

  • 100g cooked chicken breast
  • 3 tbsp corn
  • 1 tbsp feta cheese
  • 1 hass avocado
  • 2 tbsp Bolthouse Caesar dressing
  • 505 calories, 37g protein.

Harvest Chipotle Bowl

ChickenGrill,grilled,bbq,breast,meat,proteinShutterstock

This Harvest Chipotle Bowl is inspired by Mexican fast food joint, Chipotle, without all the calories.

  • 4 oz of chicken breast
  • 1/2 cup of white rice
  • Pico de gallo
  • Fajita veggies
  • 2 tablespoons of corn
  • 1/2 avocado
  • Salsa
  • 411 calories, 36g protein.

Turkey Breast Wrap

healthy turkey wrap sandwich with lettuce, tomato, onion and peppersShutterstock

This Turkey Breast Wrap offers lots of protein, fiber, and healthy fat.

  • 100g sliced turkey breast
  • 1 whole grain tortilla
  • 1/2 avocado
  • Lettuce, tomatoes, onions
  • 1 tbsp mustard
  • 1 tbsp mayonnaise
  • 469 calories, 30g protein.

Greek Chicken Wraps

Chicken,Tortilla,Wrap,With,Tomato,,Corn,,And,Various,Fresh,Vegetable,

Shutterstock

Another great wrap idea? Greek Chicken Wraps.

  • 6 oz raw chicken breast
  • 1 tsp olive oil
  • 1 tbsp Greek seasoning
  • 1 whole wheat pita
  • 2 tbsp tzatziki
  • 1/2 cup baby spinach
  • Cucumber, tomato, red onion
  • 2 tbsp feta cheese
  • 584 calories, 51g protein.

“Add chicken breast to a bowl, add the olive oil and Greek seasoning. Mix to combine. Cook chicken. To assemble, place pita on a plate and top with tzatziki, spinach, cucumber, onion, chicken, and feta. Enjoy,” she writes. And if you enjoyed this article, don't missthese 8 High-Protein Foods with Nearly Zero Calories That Melt Fat.

Fitness & Workouts

Coach Lost 95 Pounds by Taking These 6 Steps

Andrea Michelle andimichellefit
Copyright andimichellefit/Instagram
Leah Groth
By Leah GrothFeb 03, 2025
Leah Groth
Writer, Editor, and Content Creator
Leah Groth has decades of experience covering all things health, wellness and fitness related.
See Full Bio
Follow:
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Are you trying to lose weight but aren’t sure what to do? It may be as simple as implementing a few healthy habits into your routine, says one expert. Andrea Michelle is an online coach and certified personal trainer who helps “women love their bodies and get strong AF,” she writes in her Instagram bio. In a new post, she reveals what she did to lose 95 pounds. “I went from 240 lbs to 145 lbs naturally, & if I was someone who wanted to do the same in 2025, here’s what I’d do,” she captioned the post. “Steps to kickstart your weight loss journey.”

Step One: Eat in a Calorie Deficit

The first thing to do, is eat in a calorie deficit. “Calculate your TDEE (there are lots of online calculators) and ensure you are consistently eating below your maintenance requirements. This can be as little as 100- 200 calories below maintenance, as long as you are consistent you will lose fat,” she writes.

Step Two: Don’t Eliminate Foood Groups You Like

Next, don’t eliminate any food groups or foods you enjoy. “Work these foods into your meal plan, prioritize variety and plan for treats. All foods fit! If you enjoy the foods you are eating it will be much easier to stick to your deficit,” she suggests.

Step Three: Prioritize Protein

The third step is prioritizing protein. “Protein is so important while losing weight for a number of reasons. Firstly it increases satiety, keeping you fuller for longer. Secondly it boosts metabolism, it takes more energy for your body to break down protein than it does carbs or fat. Thirdly it preserves and builds muscle mass. During weight loss eating adequate protein helps your body preserve lean muscle mass, this means more of the weight you lose is fat,” she writes.

What Science Says About Protein

According to clinical trials, consuming more protein than the recommended dietary allowance not only reduces body weight (BW), but also enhances body composition by decreasing fat mass while preserving fat-free mass (FFM) in both low-calorie and standard-calorie diets.

Step Four: Have a Step Goal

Next, have a step goal. “I did no formal cardio while losing weight. Instead, I focused on increasing my NEAT (non-exercise activity thermogenesis) and had a goal of hitting at least 10 thousand steps per day. If this is a big jump for you start by increasing your steps slowly over time. Pick a step goal that is challenging but realistic,” she writes.

RELATED:8 High-Protein Foods with Nearly Zero Calories That Melt Fat.

How Many Steps?

How many steps should you walk? According to a 2018 study in Obesity, walking 10,000 steps a day is linked to weight loss and weight management. Other studies published by the Journal of American Medical Association (JAMA) in JAMA Neurology and in JAMA Internal Medicine also linked walking 10,000 steps a day to less dementia and less cardiovascular disease overall, with less heart disease, less heart failure, and fewer strokes.

Step Five: Lift Weights

“Focus on strength training regularly with progressive overload,” is step five. “Strength training is so important while losing weight because we don’t want to burn our muscle, we want to burn fat! If you strength train while in a calorie deficit you will lose less muscle than someone who isn’t exercising or only doing cardio,” she writes.

Science Supports Strength Training for Weight Loss

According to the Mayo Clinic, strength and weight training help reduce body fat, preserve and increase lean muscle mass, and burn calories more efficiently. Strength training may also help you:

  • Develop strong bones
  • Manage your weight
  • Enhance your quality of life
  • Manage chronic conditions
  • Sharpen your thinking skills.

Step Six: Be Patient

And the last step? Be patient. “Remember progress takes time. Short term fixes = short term results. Be patient with yourself and celebrate all the small wins along the way!” she writes.

See Her Before-and-After

In another recent post, Andi shared her amazing before-and-after photos. “Transformation photos will show you what I lost, but they don’t show you everything I’ve gained in the process- strength, confidence, determination, self love, discipline,” she wrote. “Photo on the left is from Oct. 2023. Photo on the right is from Sept. 2024.” And if you enjoyed this article, don't miss12-3-30 Walking Method: 20 Proven Tips to Lose Weight Faster.

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