FDA Alert: Ozempic Overdose Risks and Weight Loss Drug Safety

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        FDA Alert: Risks of Injectable Weight-Loss Drug Overdose
    Taking more Ozempic than prescribed can land you in the hospital, they warn. 
By Leah GrothAug 02, 2024
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Leah Groth has decades of experience covering all things health, wellness and fitness related. 
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By Leah GrothAug 02, 2024
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Leah Groth has decades of experience covering all things health, wellness and fitness related. 
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   Christopher Roback
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			   sound information and advice to make the smartest, healthiest choices.
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When it comes to drugs, following the recommended or prescribed dosages is crucial. While it can be tempting to take more than prescribed, it can be hazardous to your health. This week, the FDA issued an alert about Ozempic and other weight loss drugs, revealing there have been several reports of overdoses. However, instead of helping people lose more weight, taking more than recommended is resulting in some pretty serious side effects.
The FDA Has Received Several Reports of Ozempic Overdose
Shutterstock
In a press release, the FDA revealed that they have received reports of “adverse events, some requiring hospitalization, that may be related to overdoses due to dosing errors associated with compounded semaglutide injectable products.”
They maintain that people are doing it incorrectly. “Dosing errors have resulted from patients measuring and self-administering incorrect doses of the drug and health care providers miscalculating doses of the drug,” they continue. “The majority of the reports described patients mistakenly drawing up more than the prescribed dose from a multiple-dose vial during self-administration. In these instances, patients administered five to 20 times more than the intended dose of semaglutide.”
Many of the Patients Were Inexperienced with Self-Injections
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They encourage patients to talk with their healthcare provider or compounder about how to measure and administer the intended dose of compounded semaglutide.
“Many of the patients who received vials of compounded semaglutide lacked experience with self-injections, according to the adverse event reports. Unfamiliarity with withdrawing medication from a vial into a syringe coupled with confusion between different units of measurement (e.g., milliliters, milligrams, and “units”) may have contributed to dosing errors,” they say.
Providers Need to Counsel Patients
Shutterstock
FDA encourages healthcare providers and compounders to provide patients with the appropriate syringe size for the intended dose and counsel patients on how to measure the intended dose using the syringe.
Additionally, health care providers should be vigilant when prescribing and administering compounded semaglutide, as there may be different concentrations available. If uncertain, health care providers should contact the compounder about calculating the correct dose of medication to prescribe or administer.
These Are the Signs of Ozempic Overdose
Shutterstock
According to the prescribing information for FDA-approved semaglutide injection, there are several adverse effects of overdose, including severe nausea, severe vomiting and severe hypoglycemia (low blood sugar levels).
“A prolonged period of observation and treatment for overdose symptoms may be necessary due to the long half-life of semaglutide of about one week,” they add.
RELATED:20 Possible Ozempic Side Effects
Compounded Versions Are Being Marketed for Weight Loss and Are “Riskier”
Shutterstock
The FDA also reveals that there are compounded semaglutide products marketed for weight loss, which are riskier than the pure versions. “Compounded drugs pose a higher risk to patients than FDA-approved drugs because compounded drugs do not undergo FDA premarket review for safety, quality or effectiveness. Compounded drugs should only be used for patients whose medical needs cannot be met by an available FDA-approved drug,” they say.
Amongst the reports, the FDA reveals that some side effects were serious. “Some patients sought medical attention or required hospitalization. Adverse events included gastrointestinal effects (e.g., nausea, vomiting, abdominal pain), fainting, headache, migraine, dehydration, acute pancreatitis, and gallstones,” they say. If you read this article, don't miss these 20 Things You Need to Know About Ozempic and Weight Loss.
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        FDA Alert: Risks of Injectable Weight-Loss Drug Overdose
    

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By Leah GrothAug 02, 2024
Leah Groth
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Leah Groth has decades of experience covering all things health, wellness and fitness related. 
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   FACT CHECKED BY
   Christopher Roback
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Our content is fact checked by our senior editorial staff to reflect accuracy and ensure our readers get
			   sound information and advice to make the smartest, healthiest choices.
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               scientific studies and medical journals.
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When it comes to drugs, following the recommended or prescribed dosages is crucial. While it can be tempting to take more than prescribed, it can be hazardous to your health. This week, the FDA issued an alert about Ozempic and other weight loss drugs, revealing there have been several reports of overdoses. However, instead of helping people lose more weight, taking more than recommended is resulting in some pretty serious side effects.
The FDA Has Received Several Reports of Ozempic Overdose
Shutterstock
In a press release, the FDA revealed that they have received reports of “adverse events, some requiring hospitalization, that may be related to overdoses due to dosing errors associated with compounded semaglutide injectable products.”
They maintain that people are doing it incorrectly. “Dosing errors have resulted from patients measuring and self-administering incorrect doses of the drug and health care providers miscalculating doses of the drug,” they continue. “The majority of the reports described patients mistakenly drawing up more than the prescribed dose from a multiple-dose vial during self-administration. In these instances, patients administered five to 20 times more than the intended dose of semaglutide.”
Many of the Patients Were Inexperienced with Self-Injections
Shutterstock
They encourage patients to talk with their healthcare provider or compounder about how to measure and administer the intended dose of compounded semaglutide.
“Many of the patients who received vials of compounded semaglutide lacked experience with self-injections, according to the adverse event reports. Unfamiliarity with withdrawing medication from a vial into a syringe coupled with confusion between different units of measurement (e.g., milliliters, milligrams, and “units”) may have contributed to dosing errors,” they say.
Providers Need to Counsel Patients
Shutterstock
FDA encourages healthcare providers and compounders to provide patients with the appropriate syringe size for the intended dose and counsel patients on how to measure the intended dose using the syringe.
Additionally, health care providers should be vigilant when prescribing and administering compounded semaglutide, as there may be different concentrations available. If uncertain, health care providers should contact the compounder about calculating the correct dose of medication to prescribe or administer.
These Are the Signs of Ozempic Overdose
Shutterstock
According to the prescribing information for FDA-approved semaglutide injection, there are several adverse effects of overdose, including severe nausea, severe vomiting and severe hypoglycemia (low blood sugar levels).
“A prolonged period of observation and treatment for overdose symptoms may be necessary due to the long half-life of semaglutide of about one week,” they add.
RELATED:20 Possible Ozempic Side Effects
Compounded Versions Are Being Marketed for Weight Loss and Are “Riskier”
Shutterstock
The FDA also reveals that there are compounded semaglutide products marketed for weight loss, which are riskier than the pure versions. “Compounded drugs pose a higher risk to patients than FDA-approved drugs because compounded drugs do not undergo FDA premarket review for safety, quality or effectiveness. Compounded drugs should only be used for patients whose medical needs cannot be met by an available FDA-approved drug,” they say.
Amongst the reports, the FDA reveals that some side effects were serious. “Some patients sought medical attention or required hospitalization. Adverse events included gastrointestinal effects (e.g., nausea, vomiting, abdominal pain), fainting, headache, migraine, dehydration, acute pancreatitis, and gallstones,” they say. If you read this article, don't miss these 20 Things You Need to Know About Ozempic and Weight Loss.

        
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        3 New Ozempic and Wegovy Side Effects
    

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By Ferozan MastAug 19, 2024
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With 1 in 8 US adults having tried a GLP-1 drug like Ozempic or Mounjaro at some point and half of those currently using a prescription, approximately 15 million people are taking these drugs, according to a survey by KFF. With the popularity of these medications exploding, tracking side effects is more important than ever. New research published in JAMA shows that non-diabetics who take the drugs could experience serious and unpleasant side effects. Here’s what those side effects are, plus others to expect from taking a GLP-1 drug.
PancreatitisShutterstock
Non-diabetic users have a roughly nine times higher chance of developing pancreatitis. “It's definitely important that we're talking about this, but I want to keep it in perspective,” Dr. Tara Narula tells TODAY. “These drugs have been around and treating diabetic patients for over ten years, and we've really known about a lot of these side effects, bowel obstruction, pancreatitis, in fact, many of them are on the labels for these drugs.”
Bowel ObstructionNon-diabetic users have a four times higher risk of a bowel obstruction. “But the absolute risks are small, so these are rare,” Dr. Narula says. “We're talking about, for example, gastroparesis, which is this concept of slowing stomach emptying. We're talking about going from 0.3% with these non-GLP drugs to 1% with Ozempic, 0.3% to 0.8 or 0.7% with the other drugs. So these are small increases.”
RELATED:What Happens to Your Body When You Stop Taking Ozempic
Stomach ParalysisShutterstock
Non-diabetic users have a more than three-and-a-half times higher risk of stomach paralysis. “That's actually how this drug partially works, which is slowing the emptying of the stomach,” Dr. Narula says. “So it helps you feel fuller longer. The problem is, in some people, if it is severe, you will end up with nausea, vomiting, abdominal pain, feeling full bloating. So it's important we're raising awareness, but we want to keep it in perspective.”
No Off-Label DrugsShutterstock
Dr. Narula makes it clear no one should be trying to get these drugs without going through a medical professional. “People should not be getting this drug off the internet,” she says. “They should not be getting it without sitting down with a healthcare provider who can really talk to you about the risks and the benefits. Are you someone, for example, who has a history of bowel problems or pancreatitis? Then you probably shouldn't be taking this drug. Do the benefits outweigh? And yes, for obesity, we're talking about cardiovascular risks, cancer risks.”
Take It SlowShutterstock
Dr. Narula recommends starting on a low dose and increasing if necessary. “For a lot of people, there is going to be a benefit here, but you really want to do it the right way in terms of starting these drugs. Start low; you don't increase it until four to six weeks. You monitor for side effects, and if you need to, you can lower the dose. This healthcare provider should be talking to you about non-GI risks as well.”
There Are Benefits TooShutterstock
Dr. Narula says 40 to 60% of my patients are talking about GLP-1 drugs. “I mean, so many of my patients struggle with obesity, and many of them want to know about other options besides bariatric surgery and meeting with a nutritionist,” she says. “They say I've tried everything, and I can't figure out a way to lose weight. And we know that with these medications, we are seeing benefits in a cardiovascular high-risk population for lowering the risk of heart attack and stroke. So there are benefits for those people. So it is important to talk to your doctor about it. It's not for everyone. It may be for you, but really have that conversation.”
RELATED: 20 Things You Need to Know About Ozempic and Weight Loss
Vision IssuesShutterstock
Ozempic and Wegovy may also cause several other side effects, like vision issues. “It may seem strange that a drug made to help control diabetes could make your eyesight worse, but it’s something we’ve known about for a while,” says Raj K Maturi, MD. “A large clinical study suggested that there is an association between blood sugar control and worsening of diabetic retinopathy.”
HypoglycemiaShutterstock
Ozempic may cause hypoglycemia in some people. “Signs and symptoms of low blood sugar may include dizziness or lightheadedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, and feeling jittery” Ozempic makers warn.
Gallbladder IssuesShutterstock
Some people taking GLP-1 drugs may experience gallbladder issues. “Given the wide use of these drugs, these adverse events, although rare, must be considered by patients who are contemplating using the drugs for weight loss because the risk-benefit calculus for this group might differ from that of those who use them for diabetes,” according to research published in the Journal of the American Medical Association.
Thyroid CancerShutterstock
Ozempic may cause thyroid cancer, but a study shows no significant risk. “Our study covers a broad group of patients and provides strong support that GLP-1 analogs are not associated with an increased risk of thyroid cancer,” Björn Pasternak, principal researcher at the Department of Medicine at Karolinska Institutet, said in a statement.
RELATED:20 Possible Ozempic Side Effects
Ozempic FaceShutterstock
Fast weight loss may lead to a more hollowed-out look to the face, hence the term ‘Ozempic Face’. “The term is misleading because this can be a side effect of any GLP-1 drug or any other cause of rapid weight loss,” Lisa Catanese, ELS, says via Harvard Health. “If weight is lost in a more gradual way, these changes may not be as noticeable. It's the faster pace of weight loss that occurs with GLP-1 drugs that can make facial changes more obvious.”
GI IssuesShutterstock
GLP-1 drugs may cause constipation and diarrhea. “Gradual dosing while on Ozempic is crucial to mitigate the risk of severe constipation associated with higher doses,” Andrew Le, MD, tells Buoy Health. “Constipation caused by Ozempic usually subsides over time, with the median duration of constipation lasting 47 days.”
Fatigue and HeadacheShutterstock
Fatigue and headaches are also common side effects. “Gastrointestinal problems are the most common side effects since Wegovy can slow down people’s digestive systems,” Dr. Cecilia Low Wang, endocrinology, diabetes and metabolism expert, tells UC Health. “During clinical trials, some participants experienced nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, indigestion, dizziness, bloating and gas.”
RELATED: I Lost 10 Pounds in 30 Days With Walking and Eating Real Food
Severe Side EffectsShutterstock
Dr. Low Wang says side effects can be so severe some people stop taking the drug. “About one in five people might stop because they are experiencing bad side effects,” she tells UC Health. “I encourage some patients to stay at the lower dose level for a longer period of time to see if they can tolerate it better and still get some benefit from the medication. Or if they don’t tolerate this medication, we might try a different one.” And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.
Nutrition & Diet
        20 Things You Need to Know About Ozempic and Weight Loss
    

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By Leah GrothMay 12, 2024
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Leah Groth has decades of experience covering all things health, wellness and fitness related. 
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If you have any concerns about the accuracy of our content, please reach out to our editors by e-mailing
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Are you thinking about using Ozempic or another weight loss drug? Before you schedule an appointment with an MD or telemedicine doctor, educating yourself about the drug will give you a better idea of whether or not it’s worth it. Here is everything you need to know about Ozempic—how it works and its benefits for weight loss, how much it costs, and the potential side effects.
How Ozempic Works
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How exactly do weight loss drugs help you lose weight? “Ozempic enhances the release and action of insulin throughout the body, which helps with fat loss,” explains Dr. Sue Decotiis, MD, NYC weight-loss doctor.
Ozempic Shuts Down Your Appetite, and You Feel Full Faster
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“Weight loss drugs also have a tremendous effect on satiety, shutting down appetite so the patient feels very full after eating much less food,” she explains. “Ozempic acts on receptors in the gut and brain that regulate appetite.”
It Also Resets Your Rate for Fat Burning
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Ozempic also targets the centers in the brain that resets a person’s set rate for fat, Dr. Decotiis says. “When your set rate is higher for fat, you tend to hold more weight. When people go on Ozempic it resets the amount of weight that your body wants to hold onto.”
It Improves Insulin Function
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The main way Ozempic works is changing the way insulin works, explains Dr. Decotiis. “When insulin works well, you can burn fat, when it doesn’t you gain weight,” she says.
It Helps Regulate Hormones
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“It helps regulate people’s hormones that have changed due to aging, stress, etc., so that they can lose weight,” she continues. “When people age their hormones change and it’s harder for them to lose weight. Ozempic stimulate the hormones needed in the body for fat loss.”
It Can Help with Self-Esteem and Rarely Leads to Depression
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Dr. Decotiiis has seen a lot of positive effects on personality in her practice. “When people lose weight, they have better self-esteem, and they feel more confident in their own skin,” she says. “I have people who were using sedatives for anxiety or depression, and then when they took these drugs, they felt better and didn’t need them as much. My patient who had ADHD felt they had better focus and concentration. I have never had anyone who’s gone into depression or has felt worse after taking these drugs. My advice is to know who the patient is and supervise them accordingly.”
Ozempic Is Actually Only Approved for Those with Type 2 Diabetes
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According to the National Library of Medicine Ozempic is approved to control blood sugar levels in adults with type 2 diabetes when other medications do not control the sugar levels well enough.
It Can Also Help with Heart Health
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It is also used to reduce the risk of a stroke, heart attack, or death in adults who have type 2 diabetes along with heart and blood vessel disease. “It is not used to treat type 1 diabetes or diabetic ketoacidosis,” they say.
Wegovy Is Approved for Weight Loss
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“Semaglutide injection (Wegovy) is used to reduce the risk of a stroke, heart attack, or death in adults who are overweight or obese along with heart and blood vessel disease,” they say, adding that  “used along with an individualized low-calorie, low-fat diet and exercise program” it can help with weight loss “in obese adults or overweight adults who may also have high blood pressure, diabetes, or high cholesterol” and in obese children 12 years of age or older.
It Comes in a Prefilled Pen
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Semaglutide injection comes in a prefilled dosing pen injected once a week under the skin. “Use semaglutide injection on the same day each week at any time of day. You may change the day of the week that you use semaglutide as long as it has been 2 or more days (48 or more hours) since you used your last dose,” they say.
RELATED:What Happens to Your Body When You Stop Taking Ozempic
You Usually Start on a Low Dosage and Work Your Way Up
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Your doctor usually gets you started on a lower dosage, increasing it after four weeks. “Your doctor may increase your dose again after another four weeks based on your body's response to the medication,” they say.
Most Common Side Effects
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These are the most common side effects of Ozempic and Wegovy:
nausea
vomiting
diarrhea
abdominal pain
constipation
heartburn
burping
More Serious Side Effect
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There are also some potential serious side effects:
ongoing pain that begins in the upper left or middle of the stomach but may spread to the back, with or without vomiting
rash; itching; swelling of the eyes, face, mouth, tongue, or throat; or difficulty breathing or swallowing
decreased urination; or swelling of legs, ankles, or feet
vision changes
fainting or dizziness
pain in upper stomach; yellowing of skin or eyes; fever; or clay-colored stools (in those receiving semaglutide [Wegovy] for management of weight loss)
rapid heartbeat
dizziness, light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety or irritability or mood changes, hunger, weakness, or feeling jittery
RELATED:5 Foods That Maximize Weight Loss on GLP-1 Medicines, According to Coach
How Much Does Ozempic Cost?
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Just because your doctor prescribes Ozempic doesn’t mean insurance will cover it. The cost of Ozempic weighs heavily on whether your health insurance company believes that you qualify for the drug.
It’s Very Expensive Without Insurance
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Ozempic is expensive if your insurance refuses to cover it. According to GoodRX, without insurance Ozempic can cost as little as $937.98 per month and as much as $1,014 per month.
How Much Does Ozempic Cost with Insurance
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How much does it cost with insurance? Novo also offers a savings card, which enables people with private or commercial insurance to pay as little as $25 for a 1-month, 2-month, or 3-month supply of Ozempic for up to 24 months. However, many people pay more than that, with most insurance companies covering around 85 percent of the cost.
How Much Profit Are the Drug Companies Making?
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According to a study published in JAMA Network Open Trusted Source, these drugs “can likely be manufactured for prices far below current prices, enabling wider access.” Researchers from Yale University, King’s College Hospital in London, and the nonprofit Doctors Without Borders concluded that if the producers were charging $0.89 to $4.73 a month and still making a profit. This is in contrast to the nearly $1,000 per month list price charged by Novo Nordisk for Ozempic in the US.
RELATED:15 Things to Know Before Getting Ozempic for Weight Loss
What Is Rebound Weight Gain?
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After you stop taking Ozempic, there is a good chance you may gain the weight back. One study found that one year after stopping the drug, participants regained two-thirds of their prior weight loss.
Ozempic Face
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"Ozempic face" is one of the most popularized side effects of GLP-1 drugs. It’s actually a side effect of rapidly losing weight and isn’t a direct result of the drug. Losing weight fast can cause facial aging, including a hallowed look, wrinkles, and sunken eyes, explains Harvard Health.
RELATED: 15 Travel Habits That Help You Stay Fit and Lose Weight on the Go
Loose Skin and Excess Fat
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“Ozempic body” and “Ozempic butt” are two more trending terms to describe the sagging skin left behind as a result of rapid weight loss. After dropping weight fast, loose skin, pockets of stubborn fat, and stretch marks can be left behind. Treatments, including surgery, like liposuction and tummy tucks, and less invasive options, like CoolSculpting and EmSculpt Neo, as well as lasers, can help treat these conditions.
Nutrition & Diet
        Expert Reveals 5 Hidden Ozempic and Wegovy Mistakes to Avoid Now
    
Copyright Dr. Brian Yeung, ND/YouTube/Shutterstock
By Christopher RobackJan 08, 2025
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Health & Wellness Writer | Author | Exclusive Contributor at Body Network
Christopher Roback is a health and wellness writer and exclusive contributor to Body Network.
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This content references scientific studies and academic research, and is fact-checked to ensure accuracy.
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Starting Ozempic or Wegovy can feel overwhelming, and many patients make critical mistakes that could affect their results. "These medications work differently from traditional treatments, and understanding how to use them correctly is crucial," explains Dr. Brian Yeung, ND, who specialize in metabolic health. With the rising popularity of GLP-1 medications for managing diabetes and weight loss, avoiding common pitfalls becomes even more important. Here are the five key mistakes to watch out for, along with expert guidance on how to prevent them.
Skipping or Inconsistent Dosing"Consistency is crucial with GLP-1 medications," says Dr. Yeung in his video. According to Cleveland Clinic, each medication has a specific dosing schedule - some require weekly injections while others are daily. Missing doses can interrupt your progress and reduce the medication's effectiveness. Set reminders and establish a routine to stay on track.
RELATED: 20 Things You Need to Know About Ozempic and Weight Loss
Ignoring Diet and HydrationShutterstock
"Many patients don't realize these medications slow down digestion, which means you need to adjust your eating habits," Dr. Yeung points out. Cleveland Clinic confirms that GLP-1 agonists work by slowing stomach emptying and increasing feelings of fullness. Stay hydrated and focus on nutrient-rich foods to prevent potential deficiencies.
Not Monitoring Blood Sugar ProperlyShutterstock
"While these medications have a lower risk of causing hypoglycemia, regular monitoring is still essential," says Dr. Yeung. Cleveland Clinic experts warn that the risk increases when combining GLP-1s with other diabetes medications. Keep track of your blood sugar levels and know the signs of low blood sugar, which include shaking, sweating, and dizziness.
Dismissing Side EffectsShutterstock
"Some initial digestive issues are common, but they shouldn't be severe or ongoing," Dr. Yeung advises. According to Cleveland Clinic, common side effects include nausea, vomiting, and diarrhea, particularly when starting the medication or increasing the dose. Don't ignore persistent or severe symptoms - contact your healthcare provider if side effects become concerning.
RELATED:20 Possible Ozempic Side Effects
Relying Solely on MedicationShutterstock
"The biggest mistake is thinking these medications work in isolation," Dr. Yeung emphasizes. Cleveland Clinic stresses that GLP-1 agonists are just one part of a comprehensive treatment plan. Successful management requires combining medication with lifestyle changes, proper diet, and regular exercise.
Understanding Your MedicationShutterstock
Cleveland Clinic notes that GLP-1 medications work by mimicking a natural hormone that helps control blood sugar and appetite. Understanding this mechanism can help you use the medication more effectively and set realistic expectations for your treatment journey.
Tracking Progress EffectivelyShutterstock
Monitor more than just weight loss. Cleveland Clinic reports that GLP-1 medications can offer additional benefits, including improved blood pressure and better lipid profiles. Keep track of these various health markers to get a complete picture of your progress.
RELATED:What Happens to Your Body When You Stop Taking Ozempic
When to Contact Your DoctorShutterstock
Cleveland Clinic recommends maintaining regular check-ups and promptly reporting any persistent side effects or concerns about the medication's effectiveness. Don't wait until small issues become major problems. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.
Nutrition & Diet
        9 Key Differences Between Ozempic and Other GLP-1 Meds for Weight Loss
    

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By Leah GrothJun 26, 2024
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Ozempic is the buzziest drug in the weight loss world. However, it isn’t the only GLP-1 drug people are using to lose weight fast. Before you try and get a prescription, there are a lot of things you need to know about the drug, including how it works and also how it compares to similar treatments on the market. Here are ten key differences between Ozempic and other GLP-1 meds for weight loss, according to triple-board-certified plastic surgeon Leo Lapuerta, MD, The Plastic Surgery Institute of Southeast Texas.
Ozempic Isn’t Even Approved for General Weight Loss
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While Ozempic is probably the most well-known GLP-1, it isn’t technically even approved for general weight loss. “It is for the control of Type 2 diabetes,” Dr. Lapuerta reveals.
Most Weight Loss Drugs Aren’t Approved for Weight Loss
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In fact, most drugs being used for weight loss weren’t even intended for that purpose. “Most of the GLP-1 drugs like Rybelsus, Victoza, Trulicity, and Byetta are intended for the treatment of Type 2 diabetes with beneficial side effects that include weight loss,” explains Dr. Lapuerta.
RELATED:20 Possible Ozempic Side Effects
Some GLP-1s Offer Heart and Kidney Benefits
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There are other benefits to taking weight loss drugs. “Ozempic, Victoza, and Trulicity all have benefits for the heart and kidneys in addition to control of Type 2 diabetes,” says Dr. Lapuerta.
One Weight Loss Drug Is Injected Daily, Most of Them Are Weekly
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Most of the GLP-1s, including Ozempic, require a weekly injection. However, “Victoza is unique because it is injected daily rather than weekly,” says Dr. Lapuerta.
One Is Available in Oral Format
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And not all of them require a needle. “Rybelsus is the only GLP-1 that is available in oral format as all the other options are by injection only,” says Dr. Lapuerta.
RELATED:What Happens to Your Body When You Stop Taking Ozempic
Some of Them Are Approved for Weight Loss and Weight Management
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Ironically, while the most well-known of the bunch isn’t even approved for weight loss, the majority of the others are. “Wegovy, Saxenda, and Mounjaro (Tirzepatide) are GLP-1 agonists intended for weight loss and weight management rather than the treatment of Type 2 diabetes,” says Lapuerta.
Some Are More Effective Than Others
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According to Dr. Lapuerta, results vary by brand. “Wegovy typically produces 2 to 3 times the percent weight loss as Saxenda,” he maintains.
Only One of Them Includes GIP
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Mounjaro (Tirzepatide) has an edge over the competition. “It is the first GLP-1 to also include GIP, glucose-dependent insulinotropic polypeptide (GIP), another gut hormone agonist that provides better longer-term control of blood sugar as indicated by better reductions in Hemoglobin A1C levels,” says Dr. Lapuerta.
RELATED:20 Things to Avoid While on Ozempic
Some Medications Have Two Names
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Don’t let names deceive you. “Zepbound is the FDA-approved version of Mounjaro specifically for weight loss,” says Dr. Lapuerta.
Keep Reading About Ozempic
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Keep educating yourself about Ozempic. Here are 15 things you should know before getting Ozempic for weight loss. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.
Nutrition & Diet
        She Lost 30 Pounds While Eating These Popular Foods
    

        I Lost 30 Pounds While Eating These High-Protein Foods
    

        Copyright denisehamdan/TikTok
    
By Leah SuzanneMay 12, 2025
Leah Suzanne
Freelance Writer/Editor
 See Full Bio 
✓Evidence-Based
This content references scientific studies and academic research, and is fact-checked to ensure accuracy.
Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.
We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.
Denise Hamdan (@denisehamdan) is a food and fitness influencer on TikTok who regularly shares her tricks and tips on weight loss with her 71,000 followers. Hamdan lost a whopping 30 pounds by following a healthy diet and exercising. In a recent clip, she reveals her diet. “Hey y'all, here's everything I ate in one day to stay lean as someone who lost 30 pounds,” she says, revealing that she eats 1829 calories and 147 g of protein per day. Body Network’s Resident RDN, The Diet Diva, Tara Collingwood, MS, RDN, CSSD, LD/N, ACSM-CPT, a Board Certified Sports Dietitian, co-author of the Flat Belly Cookbook for Dummies, also weighs in. 

            
                Breakfast
            
            
        
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A post shared by Denise 🇵🇸 (@denisehamdan)
“I started my morning with my breakfast cocktail of oxygen and creatine. I just added the products to my showcase. So go check them out. I have my cocktail with Greek yogurt with strawberries and blueberries and a drizzle of granola,” she says. The total calories equal 157 and 14 g protein.

            
                Lunch
            
            
        
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“I'm in this phase where I eat nearly the same thing every day, and that's been scrambled eggs with cheese and spinach and some turkey bacon on the side,” she says about her lunch. “And honestly, I'm not complaining because it hits every time. Her total calories are 562 and 52 g protein.

            
                Green Smoothie
            
            
        
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Sometimes she will have a smoothie instead. “I made a cute little green smoothie and it was a little messy, but it was good regardless,” she says. 

            
                Pre-Workout Snack
            
            
        
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A post shared by Denise 🇵🇸 (@denisehamdan)
“Later, for a pre-workout snack, I made some cute little tuna crackers with the green onion and bell pepper,” she says about the snack totaling 430 calories and 28 g protein.

            
                OxyShred and Pre-Workout
            
            
        
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“Then I got to the gym and made my OxyShred and pre-workout combo before hitting cardio and abs,” she continued. “It had me sweating.”

            
                Protein Bar
            
            
        
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A post shared by Denise 🇵🇸 (@denisehamdan)
“Right after my workout I had my favorite dark chocolate pretzel protein bar,” she continued.

            
                Dinner
            
            
        
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A post shared by Denise 🇵🇸 (@denisehamdan)
“And finally for dinner I made this super easy teriyaki chicken bowl over brown rice,” she said, adding that the 560 calorie and 52 gram protein meal is “so delicious and the macros forward are amazing.”

            
                Dessert
            
            
        
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A post shared by Denise 🇵🇸 (@denisehamdan)
“Lastly, for dessert, I had some chocolate 'cause I cannot end the day without a little sweet treat,” she said about the 120 calorie sweet treat.

            
                RDN Weighs in
            
            
        I'm a Nutritionist and These 9 High-Protein Snacks Keep My Clients Full While Losing 50 PoundsCopyright Tara Collingwood
“1800-1900 calories seems like a good amount for her, but I don’t know her exact age, height, weight, or exercise level,” says Collingwood. “147 grams of protein is probably more than she needs, but it is not dangerously high.”

            
                Try Eating More Vegetables, Expert Says
            
            
        
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“I see a little bit of fruit on the yogurt and a tiny bit of spinach in eggs and peppers in tuna but overall not much veggie intake (green smoothie was green powder and not real whole veggies) which is proven with only 16 grams of fiber for her overall day,” Collingwood continues. “I would recommend increasing veggies to aim for 25 grams of fiber each day.” She also likes how often she is eating with the meals and snacks in between. “I do worry about the OxyShred. I couldn’t find on their website anywhere exactly how much caffeine is in it and having it later in the day could definitely impact sleep since caffeine has a 5 hour half-life,” she points out.
💪🔥Body Booster: How much protein should you consume per day? Aim for 0.8 to one gram per pound of bodyweight. And if you enjoyed this article, take advantage of these 15 Quick Ways to Lose Body Fat Percentage in a Week
Nutrition & Diet
        20 Things to Avoid While on Ozempic
    

        20 Things to Avoid While on Ozempic
    

        Shutterstock
    
By Leah SuzanneMay 12, 2025
Leah Suzanne
Freelance Writer/Editor
 See Full Bio 
✓Evidence-Based
This content references scientific studies and academic research, and is fact-checked to ensure accuracy.
Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.
We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.
Ozempic can be highly effective for weight loss, but there are definitely some unpleasant side effects to contend with, as the makers of the drug, Novo Nordisk, warn about. Nausea, constipation, and stomach pain are common, but avoiding certain foods and behaviors can make a difference. Here are 20 things to avoid while on Ozempic, to make the most of the medication and encourage healthy weight loss.

            
                Too Much Sugar
            
            
        ShutterstockAdded sugars, and sugary sodas, can spike blood sugar. Novo Nordisk, the maker of Ozempic and Wegovy, recommends that people avoid sugary foods while on the drug. “If you are taking medication to lower your sugar levels, it is advisable to avoid excess sugar consumption,” Dr. Dina Peralta-Reich, MD, FAAP, FOMA, tells Parade. “Failure to watch what you eat and keep your sugar levels elevated may prevent you from seeing the intended results of the medication,” she shares.”

            
                Ultra-Processed Foods
            
            
        ​2. Processed FoodsShutterstockUltra-processed foods can make side effects of Ozempic worse. “This medication slows down gastric emptying and the dense food will move much slower through your intestines, which can make you feel sick [and experience] nausea, vomiting, reflux and abdominal pain,” says Dr. Peralta-Reich. “Someone may not see the results they're looking for either.”

            
                High-Fat Foods
            
            
        ShutterstockFoods high in saturated and trans fats can make side effects of Ozempic worse. Some people complain of diarrhea and stomach pains. “I’ve seen an almost dumping syndrome-like response in people taking GLP-1s when they eat simple carbohydrates and high-fat foods,” Dr. Shauna Levy, a specialist in obesity medicine and medical director of the Tulane Bariatric and Weight Loss Center in New Orleans, tells TODAY.

            
                Sitting All Day
            
            
        Shutterstock/Prostock-studioStaying active is important while on Ozempic. Regular exercise is not only important for health, it can prevent muscle loss. The goal should be fat loss, and getting strong.

            
                Not Hydrating
            
            
        ShutterstockDon’t forget to drink your water and stay hydrated. Drinking water can help with side effects of Ozempic, especially nausea. Ozempic.com recommends drinking clear or ice-cold drinks to combat any nausea and discomfort.

            
                Too Much Alcohol
            
            
        ​Pro TipsShutterstockAvoid alcohol on Ozempic, experts advice. “One, it’s just empty calories. Two, it tends to make people make decisions that they otherwise might not make,” says Dr. Levy. “It could increase hunger, and the whole point of GLP-1s, or at least one of the points, is to decrease hunger. So it sort of negates their purpose.”

            
                Be Mindful of Portions
            
            
        ShutterstockOzempic keeps food in the stomach longer, so bigger portions can cause discomfort. “Understanding that overall portions are smaller on these medications, we want to optimize nutritional intake and consume the ‘best’ calories available,” obesity medicine physician Dr. Christopher McGowan tells TODAY. “The focus should be on lean protein, healthy fruits and vegetables, adequate fiber and adequate fluid intake.”

            
                Be Mindful of Coffee
            
            
        Shutterstock“Overall, coffee is perfectly fine to consume, but for some individuals can lead to stomach irritation,” says Dr. McGowan. “Therefore, I recommend drinking coffee in moderation, such as one to two cups a day. Patients should also be mindful of calorie-dense additives, like cream and sugar.”

            
                Don’t Skip Meals
            
            
        ShutterstockIt’s easy to skip meals when on Ozempic, but make sure you’re getting enough nutrition. Some people have even become malnourished as a result of not eating.  “It’s never healthy to not eat,” Dr. Hwang said. Dr. Janice Jin Hwang, the division chief of endocrinology and metabolism at the University of North Carolina School of Medicine tells the New York Times.

            
                Don’t Consider It a Quick Fix
            
            
        ShutterstockOzempic should be part of a long-term health plan. “It’s important to note that if you start taking either of these drugs for weight loss, your body may get used to it, establishing a new normal,” says UC Davis Health. This can cause your weight to plateau. Research has shown that if you stop taking Ozempic (or Wegovy), it's likely that you will gain back the weight you lost.”

            
                Same Unhealthy Lifestyle
            
            
        ​Don’t Drink as Much AlcoholShutterstockDon’t continue an unhealthy diet and assume it’s ok because of Ozempic. “You can likely lose weight on semaglutide medications without changing your diet and activity behaviors, but these lifestyle changes will make the treatment more effective,” Richard Siegel, MD, tells the Friedman School of Nutrition Science and Policy. “Also, we don’t know if weight loss will have the same health benefits if one does not change their behaviors.”

            
                Protect Your Health
            
            
        Most Women on GLP-1s Are Making a Few Common MistakesShutterstockSome doctors warn that taking Ozempic can make people complacent about their health. “It is important to remember that obesity is heterogenous, chronic and complex,” Vijaya Surampudi, MD, physician nutrition specialist and assistant director of the UCLA Weight Management Program (RFO), tells UCLA Health. “There is no cure for obesity. It requires lifelong treatment that’s not one size fits all.”

            
                Carbonated Beverages
            
            
        ​Soda and Sugary DrinksShutterstockOzempic slows down digestion, keeping food in your stomach for longer. This causes a feeling of fullness and some unpleasant side effects for some people like belching. Stick to still water as carbonated beverages can make stomach issues worse.

            
                Long-Term Goals
            
            
        ShutterstockIf you plan on only taking Ozempic or Wegovy for a short while, it’s likely your weight will come back on. “In one trial of Wegovy, people regained about two-thirds of the weight lost within a year of stopping the drug,” Dr. Siegel explains. “Lifestyle changes can help maintain weight loss, but it’s unusual to maintain all weight loss once you stop any weight loss medication.”

            
                Refined Carbohydrates
            
            
        ​Eat BreakfastShutterstockRefined carbohydrates tend to spike blood sugar, which is exactly what Ozempic is meant to treat. You don’t have to cut these foods out entirely, but be aware it makes it harder for Ozempic to do its job. “Foods like white bread, white rice, crackers, or even cereals may seem like better choices than foods with added sugar, but refined carbohydrates still metabolize as glucose in the body,” Christine Fallabel, MPH, tells Diabetes Strong.

            
                Watch Out For High Fiber
            
            
        ​And Improve Insulin SensitivityShutterstockWhile many green vegetables are low GI, be careful about the fiber. “If you’re not used to eating a lot of vegetables, you may experience side effects such as bloating and gas, until your body has acclimated to eating a more fiber-filled diet,” Fallabel says.

            
                Junk Food
            
            
        ​Belly Flab Strip Tip: Sugar and Fat Calories Leave Its Mark on Your BodyShutterstockJunk food—which you should be avoiding either way for weight loss purposes—often contains high levels of sodium. “Ultra-processed foods are high in sodium, saturated fats and added sugars, which contribute to a range of health problems,” Elizabeth Ko, MD, and Eve Glazier, MD, tell UCLA Health. These include an increased risk of Type 2 diabetes, cardiovascular disease, lowered immune response, certain cancers, dementia and early death.”

            
                Spicy Foods
            
            
        ShutterstockOzempic can cause acid reflux due to slow digestion. Spicy foods can make acid reflux worse, experts warn. However, if acid reflux is not an issue, people can probably enjoy spicy foods if they wish.

            
                Always See a Medical Professional
            
            
        ​The Drugs Mimic the GLP-1 Hormone Naturally Produced by the BodyShutterstockOzempic should only be prescribed by a medical professional. “Typically, I prescribe Ozempic for diabetes and have more often prescribed Wegovy for weight loss,” endocrinologist Alyssa Dominguez, MD, tells Keck Medicine. “I have used Ozempic, sometimes, off-label for weight loss, though getting insurance approval for that can be challenging.”

            
                Fried Foods
            
            
        ​3. Deep-Fried ItemsShutterstockFried, greasy foods can make Ozempic stomach issues worse. “Foods high in fat can make digestive side effects worse. Since food hangs around longer in the stomach, it has more time to cause problems,” Sarah Bullard, MS, RD, LD, tells Signos. “Some studies have shown that consuming too much fat can increase symptoms of fullness, nausea, and bloating in individuals with digestive issues and heartburn. Reducing fat intake resolved symptoms.”
💪🔥Body Booster: A whole foods Mediterranean diet is ideal while taking Ozempic.
Fitness & Workouts
        Sophie van Oostenbrugge Shares Her Routine
    

        Copyright gainsbybrains/Instagram/Shutterstock
    
By Leah SuzanneMay 11, 2025
Leah Suzanne
Freelance Writer/Editor
 See Full Bio 
✓Evidence-Based
This content references scientific studies and academic research, and is fact-checked to ensure accuracy.
Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.
We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.
Do you want to get your glutes sculpted for summer? Sophie van Oostenbrugg is a fitness trainer and the founder of the Gains with Brains app. She regularly shares workouts with her 2.4 million Instagram followers on how to burn fat and build muscle. “I grew up hearing that women should be as small as possible. That’s why I loved being able to share my bulking journey on social. I’ve done 2 bulks so far.. and I was thinking about starting and sharing a 3rd one,” she wrote in a recent post. She also revealed her “medium leg day” workout, which will help you tone up fast.

            
                She Does Multiple Leg Days a Week
            
            
        
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A post shared by Sophie van Oostenbrugge (@gainsbybrains)
“I have good news today..it’s a medium leg day!!!🫣🤭sooo I split my leg workouts & currently have lighter, medium and heavier days. this helps me with recovery, train through a variety of rep ranges and make it more enjoyable,” she explains in the post.

            
                She Does 8 to 12 Reps of Each Exercise
            
            
        
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A post shared by Sophie van Oostenbrugge (@gainsbybrains)
In the video she explains that she has “multiple leg days per week.” She goes onto reveal all of the exercises she does with “rep ranges from 8 to 12.”

            
                RDLS
            
            
        
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A post shared by Sophie van Oostenbrugge (@gainsbybrains)
“I started with RDLs, four sets of eight,” Sophie reveals. To do Romanian deadlifts, start with both legs pressed evenly on the floor. “Slightly bend knees while bending over,” says The Body Network’s Resident RDN, The Diet Diva, Tara Collingwood, MS, RDN, CSSD, LD/N, ACSM-CPT, a Board Certified Sports Dietitian. “Keep your arms pointing down toward the floor and lower with you almost touching the floor. Keep hips and shoulders square facing forward throughout the exercise. Return to standing.” She suggests repeating 10 to 12 times with the right leg and repeating on the left side. “Progression includes holding a weight in the arm pointing toward the floor,” she adds. 

            
                Sumo Squat with Kettlebell
            
            
        
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A post shared by Sophie van Oostenbrugge (@gainsbybrains)
“Then I moved on to a sumo squat with kettlebell. You know the deal, form over everything, so go slow and control the weight,” she says. Sumo squats are similar to regular squats, only you point your toes outward.

            
                Glute Bridges
            
            
        
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“Then I did glute bridges,” Sophie continues. You can do glute bridges with or without weights.

            
                Cable Step Up
            
            
        
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A post shared by Sophie van Oostenbrugge (@gainsbybrains)
Next up? Cable step ups, using an exercise block. “These are great as they help with balance and therefore they're easier to overload,” she says. 

            
                Seated Leg Curl
            
            
        
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A post shared by Sophie van Oostenbrugge (@gainsbybrains)
She sits down at a machine. “Then I did a seated leg curl,” she says.

            
                Core Exercise
            
            
        
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A post shared by Sophie van Oostenbrugge (@gainsbybrains)
“I finished with some core exercises,” Sophie concludes. “I want to get my core as strong as humanly possible so I can keep recording more intense ab workouts.”
💪🔥Body Booster: Try splitting up your workouts into light, medium, and intense days to allow your body ample time needed to recover.
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