Skip to content

20 Incredible Ozempic Success Stories

These transformations are amazing.
FACT CHECKED BY Christopher Roback

Is Ozempic the new wonder drug? Many experts believe so. Known generically as semaglutide, Ozempic mimics a naturally occurring hormone that encourages "fullness" and is highly effective for weight loss. "Obesity is an epidemic," endocrinologist Anne Peters, MD, tells Keck Medicine of USC. "Many people are obese and overweight in the United States. That causes all sorts of health problems. So, if we can help people lose weight easily and simply, why not use all the tools we have available?" These 20 people, who all lost weight thanks to Ozempic, would agree. Read on to find out more.

Michelé Lost 61 Pounds In 7 months


Michelé says Ozempic transformed her life. "Lost 28kg [61 pounds] in just 7 months with the help of Ozempic, smart eating habits, portion control, and calorie counting," she says. "Sharing my journey to inspire and motivate!"

Karkelia Lost 95 Pounds


Karkelia Mauney went from 260 pounds to 165 pounds, thanks to Ozempic. That's a stunning 95-pound weight loss! "Embracing the process, one step at a time," she says.

Kesia Lost Over 60 Pounds


Kesia Berrios has lost over 60 pounds so far and is still going strong! The influencer swears by Ozempic and motivational advice to live her best life. "Down 60 plus pounds!!!! Follow me for my weight loss journey," she says.

Linda Lost Over 57 Pounds In 5 Months


Linda Marie went from 223.4 pounds to 166 pounds in 5-6 months thanks to Ozempic. That's a very impressive 57.4 pounds. Nice work, Linda!

RELATED: 20 Things You Need to Know About Ozempic and Weight Loss

Amy Lose 160 Pounds


Amy lost 160 pounds by taking Ozempic, and doesn't regret it for a second. She posts lots of before and after shots so people can see what a drastic difference the drug has made.

Holly Lost 105 Pounds

A pair of female feet standing on a bathroom scale

Holly Figueroa O'Reilly lost 105 pounds on Ozempic after struggling with her weight most of her life. She now weighs 145 pounds. "It just completely transformed my body and the way that I conduct my life," she told TODAY.

Jen Lost 40 Pounds


Jen Alico lost 40 pounds on Ozempic, and kept the weight off even after she stopped taking the drug. "Before and throughout this entire process I maintained a healthy lifestyle, but I just found that all of a sudden my clothes were fitting better, and I was beginning to recognize myself in the mirror again," she told Newsweek. "I started to feel good and like I could function better."

Brittany Lost Over 100 Pounds


Brittany lost over 100 pounds on Mounjaro. "I might not be where I want to be yet but, I'm so much closer than I ever dreamed I would be when I started this journey 16 months ago," she captioned an Instagram post. "No, I'm not losing weight as fast as I'd like but I'm doing it in a sustainable way through moderation and movement and I feel good about that."

Almost 20 Pounds Lost In 6 Weeks

Santiago, Chile, august 16th, 2023. Pen injection of semaglutide named

Redditor loseitnoww has lost 19 pounds so far in just 6 weeks using Ozempic. "I was on 0.25mg for 4 weeks, then moved up to 0.5mg and tomorrow will be my 3rd shot of the 0.5mg. No negative side effects at all and I appear to be responding really well to this drug 👏 I'm excited to share another update in a few weeks time again. Best of luck to everybody 😊," she captioned a post.

RELATED: 20 Possible Ozempic Side Effects

Redditor Loses 69 Pounds


Redditor tbacks97 went from 205 pounds to 136 pounds in just eight months. "Today I officially hit a weight that is 'healthy' for my BMI! My life is completely changed, it is difficult to describe how freeing it is to not feel held back by movement anymore," she says.

Husband and Wife Lose 136 Pounds Combined


Redditor NefariousnessNo695 lost 66 pounds and her husband lost 70 pounds. "Within the first two days, I could breathe and my chest didn't hurt when I walked," she says. "The cardiac coverage is real. I couldn't walk 50 ft without stopping to get a breathe. Now we are at a mile and I lift or do chair yoga, tai chi, Pilates and the pool. It took a while to move but I started with chair yoga on silver sneakers on YouTube. Taking care of myself is finally my priority."

165 Pounds Down—and No Ozempic Face!


Redditor mrstruong lost a whopping 165 pounds on Ozempic. But that's not all—she also adopted many healthy habits. "100g of protein, 1500 calories a day, slowly worked my way up from not being able to tie my own shoes to walking 6km 3 to 4 times a week," she said. "People who go on and on about "ozempic face" should see your transformation!" reads a comment.

RELATED: What Happens to Your Body When You Stop Taking Ozempic

32 Pounds Down

Montreal, CA - 16 November 2023: Ozempic semaglutide injection pens. Ozempic is a medication for obesity

Redditor Last-Scratch9221 lost 32 pounds in three months on Ozempic. "I have also biked 68.7 miles this last week 🙌 I love my ebike. I don't mind taking risks and extending my distance because I know if I need it the motor is there. Today rode to drs and then up to the gym and home for a total of 20.9 miles – burned 700+ cals plus 300+ at the gym. I have so much more energy with Oz I absolutely love it."

Jacqueline Lost 90 Pounds


Jacqueline went from 271 pounds to 181 pounds on Ozempic. Her goal weight is 150 pounds. "I started by walking 30 minutes a day, and slowly added more. I really got into podcasts so I would "treat" myself to my favorite pods on my walks. Now I do 4-5 miles a day, body weight exercises, and Pilates! Just do what you can, and find exercise that you like!" she says.

Megan Lost 111 Pounds


Megan went from 251 pounds to 140 pounds. Vacation just hits so freakin' different when you FEEL good about yourself. I cannot even explain," she captioned an Instagram post. "I didn't have to 'diet' right before vacation and I didn't have to worry if any of my clothes still fit. It was freakin' glorious."

RELATED: 12 Tips to Maintain Weight Loss After Using Ozempic and GLP-1 Medications

Marcia Lost 70 Pounds


Marcia Perry, NASM – CPT, WFS, lost over 70 pounds and changed her life. "My A1C is now out of pre-diabetic range, my cholesterol and liver enzymes are normal, and I feel like me again for the first time in 10 years. The 70ish lb weight loss is just the cherry on top," she captioned an Instagram post.

Taylor Lost 40 Pounds


Taylor Kast went from 220 pounds to 180 pounds on Ozempic. "I'm 2lbs away from having lost 40 lbs since Feb 27th, 2023. I am beyond amazed at all of the changes my body has gone through," she captioned an Instagram post.

Ana Lost 59 Pounds


TikToker Ana Fontini lost 59 pounds on Ozempic. What is the average success rate for Ozempic? According to studies, it averages 5 pounds a month.

Barbie Lost 180 Pounds

Ozempic Insulin injection pen or insulin cartridge pen for diabetics. Medical equipment for diabetes parients. Copenhagen, Denmark - May 17, 2023.

Barbie Jackson-Williams lost 180 pounds on Ozempic. "I want to be active. I want to be doing stuff. I can't sit and watch TV like I used to," she told NBC News. "I used to be dead from the waist down. Very dead. But I'm not now."

RELATED: 5 Foods That Maximize Weight Loss on GLP-1 Medicines, According to Coach

Pepper lost 30 Pounds

Montreal, CA - 16 November 2023: Ozempic semaglutide injection pens and box. Ozempic is a medication for obesity

Pepper Schwartz lost 30 pounds on Ozempic. "I have really thought about this in terms of health a lot. I'm older. I just don't think I can afford to (mess) around with weight anymore," the 78-year-old told TODAY. "I love the fact that my blood pressure is low and my cholesterol is low and all those good things. Those are my motivations now rather than trying to fit in a size 4 dress."

💪🔥Body Booster: Ozempic is most effective when combined with a healthy diet and active lifestyle.

Ferozan Mast
Ferozan Mast is a science, health and wellness writer with a passion for making science and research-backed information accessible to a general audience. Read more