Skip to content
Nutrition & Diet
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

7 Things You Must Know Before Starting Semaglutide

Essential safety advice from a physician who prescribes it.

Christopher Roback
By Christopher RobackApr 27, 2025
Christopher Roback
Health & Wellness Writer | Author | Exclusive Contributor at Body Network
Christopher Roback is a health and wellness writer and exclusive contributor to Body Network.
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Christy Risinger, MD
Copyright Christy Risinger, MD/YouTube
Christopher Roback
By Christopher RobackApr 27, 2025
Christopher Roback
Health & Wellness Writer | Author | Exclusive Contributor at Body Network
Christopher Roback is a health and wellness writer and exclusive contributor to Body Network.
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Nutrition & Diet

The growing popularity of weight loss medications has created both opportunities and challenges for patients. Finding safe, effective treatments at reasonable prices isn't always straightforward. Christy Reisinger, MD, a General Internal Medicine Physician, has guided countless patients through this process. "There's been so much misinformation that's been given to the public," explains Dr. Christy, who wants to clear up confusion around these medications. Before you start semaglutide therapy, here are seven critical factors to consider for your safety and success.

Research your pharmacy thoroughly

When considering compounded semaglutide, verifying your pharmacy's credentials is non-negotiable. "I did my research, and you can too," Dr. Christy says in her post. She specifically recommends using the BeSafeRx tool to investigate potential pharmacies before making your decision. This resource reveals if a pharmacy has faced safety concerns or regulatory issues in the past. Dr. Christy even mentions, "There's actually a compounding pharmacy that I refuse to use because it's had several safety concerns."

RELATED: 15 Things to Know Before Requesting Ozempic for Weight Loss

Confirm sterile compounding practices

Pen,Injection,Semaglutide,Ozempic, diabetes, medicine, medication, diet, weight, loss​Mental Clarity and Reduced Food NoiseShutterstock

Injectable medications require strict sterile protocols to prevent contamination and infection. "Because semaglutide is an injectable medication, it needs to be made under a sterile hood in sterile conditions, and that's really important," Dr. Christy emphasizes. When speaking with your provider, specifically ask if they work exclusively with sterile compounding pharmacies. This seemingly small detail can make an enormous difference in medication safety and in reducing potential complications.

Beware of financial incentives

Pharmacy,Drugstore:,Beautiful,Asian,Pharmacist,Uses,Checkout,Counter,Computer,,Does​ How Much Lysine You Need DailyShutterstock

Your provider should have your best interests at heart, not profit motives. "I don't receive any money or kickbacks when I write a prescription for compounded semaglutide," Dr. Christy states firmly. She explains that the proper process involves patients paying pharmacies directly, with physicians receiving no financial benefit from these transactions. "If your doctor or your med spa or wherever you're getting your compounded medication is getting benefit monetarily from it, I would be wary," she cautions.

Ask about ingredient sourcing

Valparaiso, IN USA - January 22, 2024: Wegovy semaglutide pens for treatment of chronic obesity, close up​Combining Natural GLP-1 Boosters for Maximum ResultsShutterstock

Not all semaglutide is created equal, and quality control matters significantly. Dr. Christy notes that reputable "compounding pharmacies are getting semaglutide from FDA-registered facilities." This ensures pharmaceutical-grade ingredients rather than questionable alternatives. When discussing treatment with your provider, ask specifically where they recommend that you obtain semaglutide. Any hesitation or vague answers should raise immediate concerns about quality and safety.

RELATED: 20 Possible Ozempic Side Effects

Question added ingredients

Medicine,,Healthcare,And,People,Concept,-,Female,Doctor,With,Tablet​Check In Regularly with Your DoctorShutterstock

Simple formulations tend to be safer when it comes to compounded medications. "I don't add anything to semaglutide," says Dr. Christy. She explains that while some providers mix in vitamin B12 or other additives, "we don't really know how other ingredients will interact with the semaglutide." Requesting pure semaglutide without additional components can reduce potential interactions and keep your treatment protocol straightforward and easier to monitor.

Understand reasonable pricing

Young woman with wallet and money in boutique, closeupShutterstock

Affordability drives many patients toward compounded options, but extreme bargains should trigger suspicion. "Whereas Wegovy and Ozempic without a coupon cost about $1,200 a month, compounded semaglutide tends to be around $300 a month," Dr. Christy explains. She specifically warns against "bargain basement" prices, noting, "I think realistically, you should be spending a couple of hundred dollars a month to get it from a reputable compounding source." Unusually low prices often indicate corners being cut.

Consult with obesity medicine specialists

Doctor measuring obese man waist body fat. Obesity and weight loss

Shutterstock

Generic weight loss advice can't replace specialized medical expertise. "Please don't buy semaglutide from an online source without talking with knowledgeable physicians, preferably trained in obesity medicine," urges Dr. Christy. These specialists understand proper dosing protocols, potential side effects, and how to integrate medication into comprehensive treatment plans. Dr. Christy emphasizes that "there are ways to use these medications well and then there are ways to use them in an unsafe way," highlighting the importance of professional guidance.

RELATED: What Happens to Your Body When You Stop Taking Ozempic

Conclusion

Portrait of depressed woman sitting alone at home and looking away with sad expression holding hands on chin, deep thoughts feeling lonely. Frustrated blonde female pondering make difficult choice.11 Signs Ozempic Is Not for YouShutterstock

Navigating the world of weight management medications requires careful consideration of safety, quality, and proper medical supervision. By following these seven essential guidelines from Dr. Christy Reisinger, you can make more informed decisions about semaglutide treatment. Remember that even with compounded versions, professional medical oversight remains crucial throughout your treatment journey. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

glp-1

More For You

Nutrition & Diet

7 Things You Must Know Before Starting Semaglutide

Christy Risinger, MD
Copyright Christy Risinger, MD/YouTube
Christopher Roback
By Christopher RobackApr 27, 2025
Christopher Roback
Health & Wellness Writer | Author | Exclusive Contributor at Body Network
Christopher Roback is a health and wellness writer and exclusive contributor to Body Network.
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

The growing popularity of weight loss medications has created both opportunities and challenges for patients. Finding safe, effective treatments at reasonable prices isn't always straightforward. Christy Reisinger, MD, a General Internal Medicine Physician, has guided countless patients through this process. "There's been so much misinformation that's been given to the public," explains Dr. Christy, who wants to clear up confusion around these medications. Before you start semaglutide therapy, here are seven critical factors to consider for your safety and success.

Research your pharmacy thoroughly

When considering compounded semaglutide, verifying your pharmacy's credentials is non-negotiable. "I did my research, and you can too," Dr. Christy says in her post. She specifically recommends using the BeSafeRx tool to investigate potential pharmacies before making your decision. This resource reveals if a pharmacy has faced safety concerns or regulatory issues in the past. Dr. Christy even mentions, "There's actually a compounding pharmacy that I refuse to use because it's had several safety concerns."

RELATED: 15 Things to Know Before Requesting Ozempic for Weight Loss

Confirm sterile compounding practices

Pen,Injection,Semaglutide,Ozempic, diabetes, medicine, medication, diet, weight, loss​Mental Clarity and Reduced Food NoiseShutterstock

Injectable medications require strict sterile protocols to prevent contamination and infection. "Because semaglutide is an injectable medication, it needs to be made under a sterile hood in sterile conditions, and that's really important," Dr. Christy emphasizes. When speaking with your provider, specifically ask if they work exclusively with sterile compounding pharmacies. This seemingly small detail can make an enormous difference in medication safety and in reducing potential complications.

Beware of financial incentives

Pharmacy,Drugstore:,Beautiful,Asian,Pharmacist,Uses,Checkout,Counter,Computer,,Does​ How Much Lysine You Need DailyShutterstock

Your provider should have your best interests at heart, not profit motives. "I don't receive any money or kickbacks when I write a prescription for compounded semaglutide," Dr. Christy states firmly. She explains that the proper process involves patients paying pharmacies directly, with physicians receiving no financial benefit from these transactions. "If your doctor or your med spa or wherever you're getting your compounded medication is getting benefit monetarily from it, I would be wary," she cautions.

Ask about ingredient sourcing

Valparaiso, IN USA - January 22, 2024: Wegovy semaglutide pens for treatment of chronic obesity, close up​Combining Natural GLP-1 Boosters for Maximum ResultsShutterstock

Not all semaglutide is created equal, and quality control matters significantly. Dr. Christy notes that reputable "compounding pharmacies are getting semaglutide from FDA-registered facilities." This ensures pharmaceutical-grade ingredients rather than questionable alternatives. When discussing treatment with your provider, ask specifically where they recommend that you obtain semaglutide. Any hesitation or vague answers should raise immediate concerns about quality and safety.

RELATED: 20 Possible Ozempic Side Effects

Question added ingredients

Medicine,,Healthcare,And,People,Concept,-,Female,Doctor,With,Tablet​Check In Regularly with Your DoctorShutterstock

Simple formulations tend to be safer when it comes to compounded medications. "I don't add anything to semaglutide," says Dr. Christy. She explains that while some providers mix in vitamin B12 or other additives, "we don't really know how other ingredients will interact with the semaglutide." Requesting pure semaglutide without additional components can reduce potential interactions and keep your treatment protocol straightforward and easier to monitor.

Understand reasonable pricing

Young woman with wallet and money in boutique, closeupShutterstock

Affordability drives many patients toward compounded options, but extreme bargains should trigger suspicion. "Whereas Wegovy and Ozempic without a coupon cost about $1,200 a month, compounded semaglutide tends to be around $300 a month," Dr. Christy explains. She specifically warns against "bargain basement" prices, noting, "I think realistically, you should be spending a couple of hundred dollars a month to get it from a reputable compounding source." Unusually low prices often indicate corners being cut.

Consult with obesity medicine specialists

Doctor measuring obese man waist body fat. Obesity and weight loss

Shutterstock

Generic weight loss advice can't replace specialized medical expertise. "Please don't buy semaglutide from an online source without talking with knowledgeable physicians, preferably trained in obesity medicine," urges Dr. Christy. These specialists understand proper dosing protocols, potential side effects, and how to integrate medication into comprehensive treatment plans. Dr. Christy emphasizes that "there are ways to use these medications well and then there are ways to use them in an unsafe way," highlighting the importance of professional guidance.

RELATED: What Happens to Your Body When You Stop Taking Ozempic

Conclusion

Portrait of depressed woman sitting alone at home and looking away with sad expression holding hands on chin, deep thoughts feeling lonely. Frustrated blonde female pondering make difficult choice.11 Signs Ozempic Is Not for YouShutterstock

Navigating the world of weight management medications requires careful consideration of safety, quality, and proper medical supervision. By following these seven essential guidelines from Dr. Christy Reisinger, you can make more informed decisions about semaglutide treatment. Remember that even with compounded versions, professional medical oversight remains crucial throughout your treatment journey. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

Nutrition & Diet

This Doctor Reveals 5 Alternative Medications When You Can't Get Ozempic

Ozempic shutterstock_1404723482
Shutterstock
Christopher Roback
By Christopher RobackNov 14, 2024
Christopher Roback
Health & Wellness Writer | Author | Exclusive Contributor at Body Network
Christopher Roback is a health and wellness writer and exclusive contributor to Body Network.
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Struggling to find your prescribed weight-loss medication? You're not alone. With widespread shortages of popular medications like Ozempic and Wegovy, many patients are searching for alternatives. Here's what you need to know about your options, according to an experienced physician.

Dr. Christy Risinger, a Board-Certified Internal Medicine Physician with nearly two decades of experience in primary care, shares vital information about GLP-1 medications and their alternatives that could help you maintain your treatment plan.

The Evolution of Weight Loss Medications

"GLP-1 medications have been around since 2005, starting with Exenatide, also known as Byetta," explains Dr. Risinger. She notes that the early medications showed promising results: "With Byetta, people experienced about a six-pound weight loss and their blood sugar reduced by 0.9%." This marked the beginning of a revolutionary change in weight management and diabetes treatment.

RELATED: 20 Things You Need to Know About Ozempic and Weight Loss

Why Newer Medications Are Hard to Find

Pharmacy,Drugstore:,Beautiful,Asian,Pharmacist,Uses,Checkout,Counter,Computer,,DoesShutterstock

"Ozempic and Wegovy are getting so much attention because they work the best among GLP-1 medications," explains Dr. Risinger. She points out that even newer medications like Zepbound and Mounjaro have shown more impressive results: "Mounjaro reduces blood sugar by two to two and a half percent, and when rebranded as Zepbound for weight loss, patients lost a whopping average of 50 pounds, which is just incredible."

What You Need to Know About Zepbound (Tirzepatide)

Zepbound injection pen from Eli Lilly is an injectable prescription medicine that may help adults with obesity, or with excess weight (overweight) Copenhagen, Denmark - November 9, 2023.Shutterstock

Zepbound was approved for weight loss in late 2023 and contains tirzepatide as its active ingredient, according to NBC. In a head-to-head study with semaglutide published in JAMA Internal Medicine, patients taking Zepbound lost more weight - around 21% of body weight over 72 weeks compared to 15% for Wegovy users. The study analyzed records from over 41,000 adults and found consistently higher weight loss percentages with tirzepatide at 3, 6, and 12 months.

What You Need to Know About Mounjaro (Tirzepatide)

Basrah, Iraq - November 24, 2023: photo of Mounjaro Weight Loss Pen in handShutterstock

Per WebMD, Mounjaro is a prescription medication containing tirzepatide used to lower blood sugar in type 2 diabetes patients. It works by increasing insulin production when blood sugar rises, preventing liver sugar release, and slowing food absorption. The medication comes in various dose strengths from 2.5mg to 15mg in prefilled pens and requires refrigeration for storage.

Understanding Your Alternative Options

Victoza Insulin group emerging from a medication for diabetes patients. studio shot on a white background in Viktoza box. Diabetes drugs.Shutterstock

If you can't access Ozempic, Dr. Risinger outlines several alternatives: "You can talk to your doctor about earlier-generation medications like Byetta, Bydureon, and Victoza." While these medications may require daily rather than weekly injections, they can be effective interim solutions.

RELATED: 20 Possible Ozempic Side Effects

What You Need to Know About Byetta (Exenatide)

Istanbul Turkey 27 April 2024; BD Micro Fine plus Pen Needle 0.25 mm (31G) x 6 mm. It is an insulin pen needle. It is sold in boxes of 100 pieces.Shutterstock

According to WebMD, Byetta contains exenatide and is used for treating type 2 diabetes. It works through three mechanisms: stimulating insulin release after meals, preventing liver sugar release, and slowing food movement through the body. It's available in 5mcg and 10mcg prefilled pens and must be used within an hour before morning and evening meals.

What You Need to Know About Bydureon BCise (Exenatide)

BYDUREON BCise Type 2 Diabetes Treatment Insulin injection pen or insulin cartridge pen for diabetics. Medical equipment for diabetes parients. Copenhagen, USA - Jun 13, 2023Shutterstock

As described by WebMD, Bydureon BCise is an extended-release form of exenatide used for type 2 diabetes management. It's administered once weekly via a 2mg single-dose autoinjector. Like other medications in its class, it works by stimulating insulin production, controlling liver sugar release, and slowing digestion.

What You Need to Know About Victoza (Liraglutide)

Prague,Czech republic-June 27 2024: VICTOZA medication with Liraglutide active substance by Novo Nordisk, used for treatment of diabetes mellitus type 2, weight management, hyperglycemia,injectionShutterstock

According to WebMD, Victoza contains liraglutide and is prescribed for type 2 diabetes management. It's also specifically indicated to lower cardiovascular event risks in diabetic patients with heart disease. The medication functions similarly to other drugs in its class by increasing insulin production, reducing liver sugar release, and slowing digestion. It's available as an 18mg/3mL solution in pre-filled pens.

Daily vs. Weekly Options

Hands,In,Blue,Surgical,Gloves,Holding,Ozempic,Insulin,Injection,PenShutterstock

"In the short term, these medications may be fine," Dr. Risinger notes, "but realize that some of them may need to go back to daily injections instead of once a week." She explains that while they're not as potent as Semaglutide (Ozempic) or Tirzepatide (Mounjaro/Zepbound), they can still be effective.

RELATED: What Happens to Your Body When You Stop Taking Ozempic

Choosing the Right Alternative for Your Condition

Close up of a female doctor filling up an application form while consulting patientShutterstock

For diabetes management, Dr. Risinger is specific: "If you've been using Ozempic for diabetes and you're no longer able to get it, then Victoza is the next best alternative for you, but realize you have to do the injection daily."

For those using Wegovy for weight management, she advises: "Saxenda may be a good fit for you in the interim, but realize once again, this medication needs to be taken once a day."

The key is working with your healthcare provider to find the most appropriate alternative that aligns with your treatment goals and lifestyle needs. While these alternatives might require more frequent dosing, they can help maintain your progress until your preferred medication becomes available again. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

Nutrition & Diet

5 Things to Know Before Taking a GLP-1 Drug, According to a Nurse Who Takes It

Stephanie Snow stephsnow np
10 Things to Know Before Taking a GLP-1 Drug, According to a Nurse Who Takes It
Copyright stephsnow np/Instagram
Christopher Roback
By Christopher RobackApr 28, 2025
Christopher Roback
Health & Wellness Writer | Author | Exclusive Contributor at Body Network
Christopher Roback is a health and wellness writer and exclusive contributor to Body Network.
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Many of us have struggled with weight loss journeys that feel like an endless cycle of hope and disappointment. Stephanie Snow is a Weight Loss Provider, Nurse Practitioner, and Obesity Medicine specialist who has walked this path herself, using GLP-1 medications as part of her own weight loss journey. In her recent social media posts, she shares insights from both her professional expertise and personal experience. "I've been on this journey too, so I know it's not easy. As a nurse practitioner and a GLP-1 user, here are five things I wish I could tell my past self," she writes. Read on to discover what this medical professional learned firsthand about these revolutionary medications.

The Pre-Medication Mindset

Even healthcare providers get nervous about starting new treatments. "Yep. Even as a nurse practitioner, I was nervous to start a GLP-1," Stephanie admits in her post. She worried about the side effects, giving herself injections, and whether this would just be another temporary solution. Stephanie explains that her biggest concern wasn't just losing weight—it was creating sustainable change in her life.

RELATED: 15 Things to Know Before Requesting Ozempic for Weight Loss

Making a Commitment Beyond the Medication

When starting her GLP-1 journey, Stephanie made a crucial decision: "If I was going to use this tool, I was going to do the work alongside it," she shares. This meant learning proper nutrition beyond just eating less, beginning strength training despite initial discomfort, and maintaining consistency even when progress slowed. Stephanie emphasizes that success with GLP-1s isn't about perfection—it's about commitment to the process.

The Surprising Fullness Factor

Woman Refusing to Eat her Meal Feeling Full. Customer sending the dish back unhappy with the serving​Skipping MealsShutterstock

One of the most unexpected aspects of GLP-1 medications is how they affect your appetite. "One of the biggest surprises of GLP-1s is how quickly you'll feel full. It's almost like your body hits a 'stop' button," says Stephanie. This dramatic change in hunger cues requires an adjustment period. Stephanie suggests trusting your body's new signals and learning to recognize when you're genuinely satisfied—which often happens much sooner than you'd expect.

Hydration Is Non-Negotiable

Water dispenser from dispenser of home fridge, Woman is filling a glass with water from the refrigerator.​Not HydratingShutterstock

Water becomes exceptionally important when taking GLP-1 medications. "Staying hydrated is crucial on GLP-1s," Stephanie advises. Proper hydration helps manage common side effects like nausea and supports digestion as your body adapts to eating smaller portions. Stephanie recommends carrying water everywhere and making consistent hydration a top priority throughout your day.

RELATED: 20 Possible Ozempic Side Effects

Protein: Your Body's Best Support

Flat,Lay,Composition,With,Protein,Bars,On,Color,BackgroundShutterstock

As your caloric intake decreases, the quality of what you eat becomes even more critical. "Protein is your new best friend," Stephanie explains. High-protein meals and snacks help maintain energy levels, preserve muscle mass during weight loss, and create lasting feelings of fullness between meals. Stephanie suggests focusing on incorporating protein into every meal to support your body during this transition.

Embracing Imperfect Progress

Young happy beautiful woman looking in the mirror satisfied with the results of her training.5 Ways to Look Better in BedShutterstock

The weight loss journey with GLP-1s isn't always smooth. "Some days you'll feel amazing, and other days might feel like a struggle. That's completely normal," Stephanie reassures. Progress rarely follows a perfect linear path, and acknowledging this reality helps build resilience. Stephanie encourages patients to practice self-compassion during challenging days rather than viewing setbacks as failures.

The Power of Patience

Santiago, Chile, august 16th, 2023. Pen injection of semaglutide named \u201cozempic\u201d, is a diabetes medicine to improve blood sugar​And Now, Some Are Recommending MicrodosingShutterstock

While GLP-1 medications have shown impressive results for many users, they're not an overnight solution. "GLP-1s work, but they're not magic!" Stephanie emphasizes. Sustainable weight loss requires time, consistency, and realistic expectations. Stephanie reminds us that the most successful outcomes come from viewing these medications as tools within a broader lifestyle change rather than quick fixes.

RELATED: What Happens to Your Body When You Stop Taking Ozempic

Finding Your Support System

Female doctor filling patient insurance information​Consult with Your DoctorShutterstock

Starting a GLP-1 medication can feel overwhelming, especially when managing side effects or adjusting to new eating patterns. "If you're feeling nervous too, I see you. Even the pros get nervous. You're not alone," says Stephanie. She highlights the importance of finding healthcare providers who understand GLP-1 medications and connecting with others on similar journeys for emotional support and practical advice. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

Nutrition & Diet

11 Things to Know Before Taking Ozempic

Dr Sophie GP
Copyright Dr Sophie GP/YouTube
Christopher Roback
By Christopher RobackMar 31, 2025
Christopher Roback
Health & Wellness Writer | Author | Exclusive Contributor at Body Network
Christopher Roback is a health and wellness writer and exclusive contributor to Body Network.
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

We've all been there - trying diet after diet, exercise plan after exercise plan, only to find ourselves struggling to lose weight or keep it off. If you've been wondering about those "miracle" weight loss drugs like Wegovy and Ozempic that celebrities are raving about, you're not alone. Dr. Sophie Newton breaks down exactly how these medications work and what you should consider before jumping on the bandwagon. Read on to discover if these treatments could be the kickstart to your weight loss journey that you've been looking for.

Yes, They Actually Work

"These medications have shown impressive results in clinical trials," Dr. Sophie says in her post. "In randomized double-blind control trials, people using Wegovy lost an average of 12% more body fat compared to those in the placebo group." Dr. Sophie explains that colleagues in the United States report excellent outcomes with patients successfully losing weight and maintaining it while on the medication.

RELATED: 15 Things to Know Before Requesting Ozempic for Weight Loss

The Celebrity Connection

Khloe Kardashian at the Cosmopolitan's 50th Birthday Celebration held at the Ysabel in West Hollywood, USA on October 12, 2015.

Shutterstock

"High-profile individuals like Elon Musk and reportedly Khloe Kardashian have used these medications for weight loss," notes Dr. Sophie. She mentions that this celebrity endorsement has led to the medication being nicknamed "the skinny shot" and has dramatically increased public interest in these treatments.

How These Drugs Actually Work

Valparaiso, IN USA - January 22, 2024: Wegovy semaglutide pens for treatment of chronic obesity, close up​Combining Natural GLP-1 Boosters for Maximum ResultsShutterstock

"These medications belong to a group called GLP-1 analogues," Dr. Sophie explains. "Wegovy contains semaglutide, which essentially makes you feel less hungry and more easily full, so you naturally eat less and lose weight." Dr. Sophie clarifies that the mechanism is straightforward and typically very effective for most patients.

Health Benefits Beyond Weight Loss

Man having chest pain - heart attack, outdoors​Myth 4: Fat Is Bad For Your HeartShutterstock

"When losing weight with these medications, you're also reducing your risk of conditions like type 2 diabetes and heart disease," Dr. Sophie points out. She highlights that the drugs help lower metabolic risk factors, providing substantial health benefits beyond mere cosmetic improvements.

RELATED: 20 Possible Ozempic Side Effects

Common Side Effects to Expect

Woman bending over toilet and having a nausea, vomit, vomitting, sick, bathroom

Shutterstock

"Like all medications, these drugs come with potential side effects," warns Dr. Sophie. "Most commonly, patients might experience nausea, vomiting, diarrhea, constipation, bloating, or excess gas." Dr. Sophie notes that these symptoms typically settle as the body adjusts, and treatment usually starts with a lower dose that gradually increases.

Serious Side Effects to Be Aware Of

Endocrinologist examining throat of young woman in clinic. Women with thyroid gland test . Endocrinology, hormones and treatment. Inflammation of the sore throat

Shutterstock

"If you have a personal or family history of thyroid cancer, these medications aren't suitable for you due to a potential link," cautions Dr. Sophie. She adds that in some cases, the medications have been associated with pancreatitis, though most people tolerate the treatment well despite these risks.

Accessibility and Cost Considerations

Montreal, CA - 16 November 2023: Ozempic semaglutide injection pens. Ozempic is a medication for obesity​These Were Game ChangersShutterstock

"While these drugs are approved by NICE on the NHS, they're only available through specialist weight loss centers, which aren't accessible to everyone," Dr. Sophie explains. She points out that many people must pay privately, creating a financial barrier that might prevent some from accessing this treatment option.

RELATED: What Happens to Your Body When You Stop Taking Ozempic

It's Not a Forever Solution

,Plus,Size,Women,Jogging,Obesity,overweight,happy,celebrate,run,running,fat​Creating Sustainable HabitsShutterstock

"You can regain weight after stopping the medication unless you maintain the lifestyle changes you've implemented," Dr. Sophie advises. She recommends thinking of these drugs as a kickstart to healthier habits rather than a permanent solution, emphasizing the importance of continued diet and exercise modifications.

A Comprehensive Approach Is Still Necessary

Healthy food at home. Happy woman is preparing the proper meal in the kitchen.​DinnerShutterstock

"While using these medications, you still need to focus on improving your diet, lifestyle, and increasing physical activity," Dr. Sophie stresses. She reminds patients that the drugs work best as part of a comprehensive approach to weight management that includes all the fundamentals you already know about.

Last Word

ozempic wegovyWegovy vs Ozempic: Pros and Cons for Weight Loss TreatmentShutterstock

If you're considering weight loss medications like Wegovy or Ozempic, remember they're most effective when combined with lifestyle changes. While they can provide an excellent starting point for your weight loss journey, sustainable results require ongoing commitment to healthy habits. Always consult with your healthcare provider to determine if these treatments are appropriate for your specific situation and health history. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

Nutrition & Diet

Mom of 4 Lost 55 Pounds on Semaglutide "Now I Finally See Myself in the Mirror"

Karli_Sine11
Copyright karli.sine/Instagram/Shutterstock
Christopher Roback
By Christopher RobackDec 29, 2024
Christopher Roback
Health & Wellness Writer | Author | Exclusive Contributor at Body Network
Christopher Roback is a health and wellness writer and exclusive contributor to Body Network.
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Standing in front of the mirror and seeing a stranger stare back – that's how Karli Sine felt after having four boys in quick succession. Between multiple pregnancies and PCOS, this Utah mom watched her weight climb to 195 pounds despite trying everything from keto to crash diets. Then she discovered semaglutide. In just five months, Karli lost 55 pounds and, more importantly, found herself again. Whether you're considering semaglutide or just starting your journey, her candid story reveals what doctors might not tell you about life on a GLP-1.

The Breaking Point: Why Another Diet Wasn't the Answer

"When I met my husband, I had just lost 16 pounds doing keto and weighed 180 at 5'9"," Karli shares in her post. But four pregnancies changed everything. "I had my first baby in 2017, did keto again, and lost 15 pounds. Then, I got pregnant with my second, third, and fourth. I never lost the weight – it just kept piling on."

The struggle became overwhelming. "I started just wearing tents for clothing. There was no other option for me. At least it didn't feel like there was," she recalls. "Even when I would get ready, I didn't feel like I looked like myself. It was a really hard time."

RELATED: 20 Things You Need to Know About Ozempic and Weight Loss

Starting Semaglutide: The First Month Truth

Finding reliable information wasn't easy. "I had heard about it from a friend, but there wasn't really anyone talking about it online," Karli explains. Even her doctor seemed uncertain: "When I asked him, he was kind of like, 'Yeah, I've heard about it, don't know much about it.' It made me not feel very confident."

She started cautiously: "I began with 10 units for two weeks, then 20 units for six weeks," she details. The journey wasn't smooth. "The first week, I felt nothing. Then, the second week, two days after my shot, I got really sick. But it wasn't like pregnancy sickness – I could take a Zofran and the nausea would go away."

The Adjustment Period: What Nobody Tells You

"Week two to week five, I was wildly tired," Karli admits. "It was really hard for me to take care of my kids just because I wanted to sleep all day long." But she persevered, gradually increasing her dose: "I went up slowly - 25, 30, 35, and then 40 for a minute, then hit 50, before starting to go backwards."

The key was finding a sustainable routine. "Semaglutide can slow your gastric system," she explains. "When I would wake up, I would have a protein shake or eggs – something that was going to sustain me. I was drinking water wildly, which isn't like me. I'm a soda girl, but I couldn't even get myself to drink soda while on this."

Beyond the Scale: Unexpected Changes

The medication's impact went far beyond weight loss. "It helped so much with my PCOS," Karli shares. "My period ended up different, but better. A lot of my inflammation went down in my joints." Even her habits changed: "My online shopping plummeted. I just had no desire. There are studies showing that once people start semaglutide, some of their bad habits kind of go away."

RELATED: 20 Possible Ozempic Side Effects

Finding Your Support System

The journey highlighted the importance of community. "In a weight loss journey, it's hard to find someone you're comfortable with, someone who can hold you accountable," Karli reflects. "This scenario with medication is different – it's more of an adjustment period."

She encourages openness: "There's a whole group of people who are like, 'Oh, I don't really want to tell people that I'm on it.' You don't have to tell anyone, but telling people helped me with my support."

The Maintenance Strategy That Works

After reaching 139 pounds – surpassing her goal of 140 – Karli focused on sustainability. "I went from weekly to biweekly, and then after a few months, to monthly," she explains. "While I don't want to be on it forever, it's really changed my life. I'm at a super tiny dose right now, and monthly has been great for me."

Looking Ahead: The Next Chapter

Success with semaglutide opened new possibilities. "Now for 2024, I'm onto a whole new journey of building muscle," Karli shares. "Finally, I feel that I'm at the capacity to take this on."

The transformation went deeper than physical changes. "Looking in the mirror and saying, 'That's how I have viewed myself my whole life, but it's not what other people were seeing' – that's been the best part," she reflects. "I know that my body and image isn't what's most important, but it's really nice to feel that it reflects what's in my head. I've gained so much more confidence back and feel like a different person."

RELATED: What Happens to Your Body When You Stop Taking Ozempic

Final Advice

Her final advice remains encouraging: "Whether the decision is to do it or not, do what's best for you. Hopefully, this will make you feel more like you. I'm proud of you." And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

Nutrition & Diet

15 Daily Habits to Lose 5-10 Pounds in 30 Days

Beautiful woman checking her body shape in a mirror.
15 Daily Habits to Lose 5-10 Pounds in 30 Days
Shutterstock
Leah Suzanne
By Leah SuzanneMay 12, 2025
Leah Suzanne
Freelance Writer/Editor
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Depending on your starting weight, losing five to 10 pounds in a month is possible to do in a healthy way. Making a few specific lifestyle and dietary changes and sticking to them will positively impact overall health as well as encourage weight loss. “The foundation of successful weight loss remains a healthy, calorie-controlled diet combined with increased physical activity,” says the Mayo Clinic. “For successful, long-term weight loss, you must make permanent changes in your lifestyle and health habits.” Here are 15 daily habits shown to help lose up to ten pounds in 30 days.

Eliminate Empty Calories

People clinking glasses with wine on the summer terrace of cafe or restaurantShutterstock

Alcohol is full of empty calories, so it’s best to cut down or simply stop drinking it altogether. Every calorie counts when you’re trying to lose weight, so make sure you use those calories to fill your body with healthy, nutrient-dense choices. Drinking too much also disrupts sleep.

Are You Actually Hungry?

Man eats, eating​What To Do InsteadShutterstock

Eat when you’re hungry, and only when you’re hungry. “Listening to your hunger works much better than relying on willpower,” Kayla Kopp, RD, LD, tells the Cleveland Clinic. “When you’re tempted to overeat, have a conversation with yourself: Are you feeling hungry, are you bored or are you feeling emotional? Will eating right now get you closer to your goal?”

Work Out First Thing

Close up woman hand doing push ups exercise in a gym in morning, sunlight effect.​Progress to Full Push-upsShutterstock

Working out first thing in the morning means you don’t have to make time for it later. It also starts the day off on a good note. No excuses!

Don’t Skip Breakfast

Healthy,Breakfast,Toast,Avocado,SmashShutterstock

Studies show people who eat breakfast (provided it’s a healthy one) make better food choices for the rest of the day. "Studies have found that although people who skip breakfast eat slightly fewer calories during the day, they tend to have higher body mass index, or BMI," Christy C. Tangney, PhD, tells Rush University Medical Center.

Take the Stairs

Determined woman running up on seaside mountain stairs​Regular ExerciseShutterstock

Walk as much as possible—park away from the grocery store entrance and take the stairs when possible. Walking will encourage fat burning and mental wellness, and you can do it throughout the day, no equipment needed.

Count Your Calories

Calories Nutrition Food Exercise ConceptShutterstock

This one is boring but crucial—to lose weight, you need to take in less calories than you’re burning off. “For example, to lose 1 to 2 pounds a week — a rate that experts consider safe — your food consumption should provide 500 to 1,000 calories less than your total weight-maintenance calories,” says Harvard Health.

Try Intermittent Fasting

Skip breakfast concept with no symbol and clock on plate, Intermittent FastingShutterstock

Intermittent fasting can be a powerful weight loss tool for some. “The weight loss effects of time-restricted eating derive primarily from achieving a negative energy balance,” Richard Joseph, MD, tells Harvard Health. “If you maintain your regular diet and then limit the time window during which you eat, it is likely that you will eat a few hundred fewer calories per day.”

No Nighttime Snacking

woman eats sweets at night to sneak in a refrigerator. Fridge​Breaking Free from Food ObsessionShutterstock

Snacking can undermine your healthy eating weight loss plan. “Try to eat most of your daily calories before sitting down to relax for the night,” Kopp tells the Cleveland Clinic. “Many of us have a tendency to overeat without thinking about it while we watch TV after dinner, and we tend to forget just how much we’ve had before calling it a night.”

Be Picky About Carbs

Healthy Food: Best Sources of Carbs on a wooden table. Top viewTop 5 Clean Carbs for Your BodyShutterstock

You don’t have to eliminate carbs—but be choosy about them. “Not all carbohydrates are created equal,” says Corewell Health. “Eating a slice of white bread won’t give your body the same nutrition as eating a slice of whole grain bread. When you’re looking for options for carbohydrates, look at the ingredients. If the first ingredient is a whole grain (like whole wheat), you’re going in the right direction.”

Eliminate Temptation

Fast food concept. Unhealthy food. Unhealthy food and fast food with donuts, chocolate, burgers and sweets top view​Hopping “On and Off” the WagonShutterstock

Keep junk food out of sight and out of mind. “Don’t keep problem foods around the house and/or at work,” says UC Davis Health. A problem food is a food that you are likely to eat too much of or too often if readily available.”

Get Enough Sleep

Top View Home: Handsome Young Man Sleeps in His Bed in a Stylish Bedroom, Sun Shines on Him. Morning Concept. Peaceful Sleeping and Relaxation, Important for Wellness . Top Down Above ShotShutterstock

Sleep is important for weight loss. “No one can make mindful food choices when they’re tired. Even missing an hour of sleep can increase your appetite because your body is craving that energy and food is fuel for your body,” psychologist Susan Albers, PsyD, tells the Cleveland Clinic. “You need a clear, focused head to make healthier food choices.”

Lift Weights

,Bodybuilder,Training,Gym:,Chest,-,Barbell, bench, press, weights, gym,exerciseShutterstock

“Resistance training can also be a really effective way of losing weight," Tessa Strain, physical activity epidemiologist at the University of Cambridge, tells The Telegraph. “All weight loss comes down to a calories in/calories out equation. resistance training is a really effective way of losing weight because you’re expending energy, which involves burning calories.”

Manage Stress

woman sitting down, his face unsettled. At the computer desk she has headaches and stress. Cause of hard work and insufficient rest.​Stress Leads to Belly FatShutterstock

Stress can undermine your weight loss efforts. “More commonly, people turn to — or away from — food as a way to help deal with stress,” says Penn Medicine. “Your metabolism can change if you regularly eat large amounts of food or don’t eat enough or at all.”

No Junk Food

,Coffee,Drive,Thru,Counter.Drive,Through,fast,food,junk,burger,friesShutterstock

Ultra-processed foods are terrible for weight loss. Not only will they not fill you up, they could make you hungrier. “Processed and fast foods contain enhanced ingredients that hit the dopamine center in your brain and make you want more,” Dr. Albers tells the Cleveland Clinic. “They are designed to be addictive to the brain.”

Drink More Water

Fitness woman drinking water from bottle. Muscular young female taking a break from workout outside.​HydrateShutterstock

Choose water over high-calorie drinks. “Sometimes we respond to thirst signals by eating — when actually what our bodies want is water,” Dr. Albers explains. “It’s easy to confuse our thirst and hunger signals, or to override thirst signals.”

💪🔥Body Booster: Focusing on long-term health and wellness will make weight loss easier.

Fitness & Workouts

The Simple Walking Routine That Helped Me Lose 40 Pounds

Alexandra_alexx.fitt
This Woman Lost 40 Pounds After Quitting These 5 Common Habits Forever
alexxandra.fitt/Instagram
Leah Suzanne
By Leah SuzanneMay 12, 2025
Leah Suzanne
Freelance Writer/Editor
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Can you lose a significant amount of weight just by walking every day? Yes, absolutely! Not only does walking burn fat, help lower blood pressure, and improve cholesterol levels, but it also does wonders for your mental state as well. “You need to make it part of your routine,” exercise physiologist Katie Lawton, MEd. tells Cleveland Clinic Health Essentials. “This is about adjusting your lifestyle for your health.” TikTok influencer Alex ( @alex.fitt) lost 40 pounds just by walking—here’s how she did it.

Don’t Start Big

@alexx.fitt Step by step walk it off #walking #weightloss ♬ original sound - alexx.fitt

Alex makes the important point that it’s better to start off slow to build sustainable habits. You don’t have to kickstart your fitness regimen with two-hour walks. Even just half an hour will make a difference to your mood and your health, and encourage you to do it again the next day.

Walking After Meals

Alex says she started off her walking program by simply taking a 15 minute walk after a big meal. Research shows walking after meals can benefit blood sugar. “Exercise impacts your blood sugar quickly, often within a few minutes,” Shannon Knapp, MEd, BSN, RN, CDCES, tells the Cleveland Clinic. “And over time, physical activity helps your body use insulin more effectively, decreasing the insulin resistance we often see in diabetes.”

Walking In the Morning

Alex would start her day with a walk. “Getting outside gives you a chance to enjoy fresh air and nature,” says Henry Ford Health. “Walking, like any form of exercise, reduces stress and anxiety. You’ll start the day with a positive attitude, better able to manage challenges during the day.”

Long Walk After Dinner

Alex would save her long walk for after dinner, which studies show is very beneficial. “The closer we get to the evening, the less efficient our bodies are at using insulin to deal with blood glucose, making it harder to keep blood glucose levels healthy,” Dr Evelyn Parr from the Australian Catholic University’s Exercise and Nutrition Research Program tells the Sydney Morning Herald. “Yet this is when we have our biggest meal of the day.”

Smaller Waist

Alex says the biggest difference she noticed from walking was in her waist. “The faster, farther and more frequently you walk, the greater the benefits,” says the Mayo Clinic. “For example, you may start out as an average walker, and then work your way up to walking faster and walking a mile in a shorter amount of time than an average walker, similar to power walkers.”

Using Technology

Alex was thrilled the first time her watch buzzed when she hit 10k steps. Research shows people who track their fitness tend to be successful. “We’ve seen this rise of digital health tools in the last decade, and they provide a great way for people to access interventions to better their health,” Michele Patel, PhD, tells Stanford Medicine.

10,000 Steps a Day

No matter how long or short her walks, Alex always aims for 10,000 steps every day. “Evidence suggests that accumulating up to 10,000 steps per day is helpful for reducing chronic conditions such as cardiovascular disease, type 2 diabetes, and some forms of cancer,” John M. Jakicic, Ph.D, tells University of Kansas Medical Center. “And more recent evidence supports the benefits of reducing the risk of dementia.”

💪🔥Body Booster: Start slow and steady to build lasting habits. Even 10 minutes will make a difference.

Nutrition & Diet

She Lost 30 Pounds While Eating These Popular Foods

Denise Hamdan denisehamdan
I Lost 30 Pounds While Eating These High-Protein Foods
Copyright denisehamdan/TikTok
Leah Suzanne
By Leah SuzanneMay 12, 2025
Leah Suzanne
Freelance Writer/Editor
See Full Bio
✓Evidence-Based

This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our team of licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

We are committed to bringing you researched, expert-driven content to help you make more informed decisions around food, health, and wellness. We know how important making choices about your overall health is, and we strive to provide you with the best information possible.

Denise Hamdan (@denisehamdan) is a food and fitness influencer on TikTok who regularly shares her tricks and tips on weight loss with her 71,000 followers. Hamdan lost a whopping 30 pounds by following a healthy diet and exercising. In a recent clip, she reveals her diet. “Hey y'all, here's everything I ate in one day to stay lean as someone who lost 30 pounds,” she says, revealing that she eats 1829 calories and 147 g of protein per day. Body Network’s Resident RDN, The Diet Diva, Tara Collingwood, MS, RDN, CSSD, LD/N, ACSM-CPT, a Board Certified Sports Dietitian, co-author of the Flat Belly Cookbook for Dummies, also weighs in.

Breakfast

“I started my morning with my breakfast cocktail of oxygen and creatine. I just added the products to my showcase. So go check them out. I have my cocktail with Greek yogurt with strawberries and blueberries and a drizzle of granola,” she says. The total calories equal 157 and 14 g protein.

Lunch

“I'm in this phase where I eat nearly the same thing every day, and that's been scrambled eggs with cheese and spinach and some turkey bacon on the side,” she says about her lunch. “And honestly, I'm not complaining because it hits every time. Her total calories are 562 and 52 g protein.

Green Smoothie

Sometimes she will have a smoothie instead. “I made a cute little green smoothie and it was a little messy, but it was good regardless,” she says.

Pre-Workout Snack

“Later, for a pre-workout snack, I made some cute little tuna crackers with the green onion and bell pepper,” she says about the snack totaling 430 calories and 28 g protein.

OxyShred and Pre-Workout

“Then I got to the gym and made my OxyShred and pre-workout combo before hitting cardio and abs,” she continued. “It had me sweating.”

Protein Bar

“Right after my workout I had my favorite dark chocolate pretzel protein bar,” she continued.

Dinner

“And finally for dinner I made this super easy teriyaki chicken bowl over brown rice,” she said, adding that the 560 calorie and 52 gram protein meal is “so delicious and the macros forward are amazing.”

Dessert

“Lastly, for dessert, I had some chocolate 'cause I cannot end the day without a little sweet treat,” she said about the 120 calorie sweet treat.

RDN Weighs in

tara collingwoodI'm a Nutritionist and These 9 High-Protein Snacks Keep My Clients Full While Losing 50 Pounds

Copyright Tara Collingwood

“1800-1900 calories seems like a good amount for her, but I don’t know her exact age, height, weight, or exercise level,” says Collingwood. “147 grams of protein is probably more than she needs, but it is not dangerously high.”

Try Eating More Vegetables, Expert Says

“I see a little bit of fruit on the yogurt and a tiny bit of spinach in eggs and peppers in tuna but overall not much veggie intake (green smoothie was green powder and not real whole veggies) which is proven with only 16 grams of fiber for her overall day,” Collingwood continues. “I would recommend increasing veggies to aim for 25 grams of fiber each day.” She also likes how often she is eating with the meals and snacks in between. “I do worry about the OxyShred. I couldn’t find on their website anywhere exactly how much caffeine is in it and having it later in the day could definitely impact sleep since caffeine has a 5 hour half-life,” she points out.

💪🔥Body Booster: How much protein should you consume per day? Aim for 0.8 to one gram per pound of bodyweight. And if you enjoyed this article, take advantage of these 15 Quick Ways to Lose Body Fat Percentage in a Week

Copyright 2025 Galvanized Media. All Rights Reserved. Body Network is part of the Dotdash Meredith Publishing Family.