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This Doctor Reveals 5 Alternative Medications When You Can't Get Ozempic

A physician shares effective alternatives.

Struggling to find your prescribed weight-loss medication? You're not alone. With widespread shortages of popular medications like Ozempic and Wegovy, many patients are searching for alternatives. Here's what you need to know about your options, according to an experienced physician.

Dr. Christy Risinger, a Board-Certified Internal Medicine Physician with nearly two decades of experience in primary care, shares vital information about GLP-1 medications and their alternatives that could help you maintain your treatment plan.

The Evolution of Weight Loss Medications

"GLP-1 medications have been around since 2005, starting with Exenatide, also known as Byetta," explains Dr. Risinger. She notes that the early medications showed promising results: "With Byetta, people experienced about a six-pound weight loss and their blood sugar reduced by 0.9%." This marked the beginning of a revolutionary change in weight management and diabetes treatment.

RELATED: 20 Things You Need to Know About Ozempic and Weight Loss

Why Newer Medications Are Hard to Find

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"Ozempic and Wegovy are getting so much attention because they work the best among GLP-1 medications," explains Dr. Risinger. She points out that even newer medications like Zepbound and Mounjaro have shown more impressive results: "Mounjaro reduces blood sugar by two to two and a half percent, and when rebranded as Zepbound for weight loss, patients lost a whopping average of 50 pounds, which is just incredible."

What You Need to Know About Zepbound (Tirzepatide)

Zepbound injection pen from Eli Lilly is an injectable prescription medicine that may help adults with obesity, or with excess weight (overweight) Copenhagen, Denmark - November 9, 2023.
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Zepbound was approved for weight loss in late 2023 and contains tirzepatide as its active ingredient, according to NBC. In a head-to-head study with semaglutide published in JAMA Internal Medicine, patients taking Zepbound lost more weight – around 21% of body weight over 72 weeks compared to 15% for Wegovy users. The study analyzed records from over 41,000 adults and found consistently higher weight loss percentages with tirzepatide at 3, 6, and 12 months.

What You Need to Know About Mounjaro (Tirzepatide)

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Per WebMD, Mounjaro is a prescription medication containing tirzepatide used to lower blood sugar in type 2 diabetes patients. It works by increasing insulin production when blood sugar rises, preventing liver sugar release, and slowing food absorption. The medication comes in various dose strengths from 2.5mg to 15mg in prefilled pens and requires refrigeration for storage.

Understanding Your Alternative Options

Victoza Insulin group emerging from a medication for diabetes patients. studio shot on a white background in Viktoza box. Diabetes drugs.
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If you can't access Ozempic, Dr. Risinger outlines several alternatives: "You can talk to your doctor about earlier-generation medications like Byetta, Bydureon, and Victoza." While these medications may require daily rather than weekly injections, they can be effective interim solutions.

RELATED: 20 Possible Ozempic Side Effects

What You Need to Know About Byetta (Exenatide)

Istanbul Turkey 27 April 2024; BD Micro Fine plus Pen Needle 0.25 mm (31G) x 6 mm. It is an insulin pen needle. It is sold in boxes of 100 pieces.
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According to WebMD, Byetta contains exenatide and is used for treating type 2 diabetes. It works through three mechanisms: stimulating insulin release after meals, preventing liver sugar release, and slowing food movement through the body. It's available in 5mcg and 10mcg prefilled pens and must be used within an hour before morning and evening meals.

What You Need to Know About Bydureon BCise (Exenatide)

BYDUREON BCise Type 2 Diabetes Treatment Insulin injection pen or insulin cartridge pen for diabetics. Medical equipment for diabetes parients. Copenhagen, USA - Jun 13, 2023
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As described by WebMD, Bydureon BCise is an extended-release form of exenatide used for type 2 diabetes management. It's administered once weekly via a 2mg single-dose autoinjector. Like other medications in its class, it works by stimulating insulin production, controlling liver sugar release, and slowing digestion.

What You Need to Know About Victoza (Liraglutide)

Prague,Czech republic-June 27 2024: VICTOZA medication with Liraglutide active substance by Novo Nordisk, used for treatment of diabetes mellitus type 2, weight management, hyperglycemia,injection
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According to WebMD, Victoza contains liraglutide and is prescribed for type 2 diabetes management. It's also specifically indicated to lower cardiovascular event risks in diabetic patients with heart disease. The medication functions similarly to other drugs in its class by increasing insulin production, reducing liver sugar release, and slowing digestion. It's available as an 18mg/3mL solution in pre-filled pens.

Daily vs. Weekly Options

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"In the short term, these medications may be fine," Dr. Risinger notes, "but realize that some of them may need to go back to daily injections instead of once a week." She explains that while they're not as potent as Semaglutide (Ozempic) or Tirzepatide (Mounjaro/Zepbound), they can still be effective.

RELATED: What Happens to Your Body When You Stop Taking Ozempic

Choosing the Right Alternative for Your Condition

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For diabetes management, Dr. Risinger is specific: "If you've been using Ozempic for diabetes and you're no longer able to get it, then Victoza is the next best alternative for you, but realize you have to do the injection daily."

For those using Wegovy for weight management, she advises: "Saxenda may be a good fit for you in the interim, but realize once again, this medication needs to be taken once a day."

The key is working with your healthcare provider to find the most appropriate alternative that aligns with your treatment goals and lifestyle needs. While these alternatives might require more frequent dosing, they can help maintain your progress until your preferred medication becomes available again. And if you enjoyed this article, don't miss 20 Incredible Ozempic Success Stories of All Time.

Christopher Roback
Professional Health and Wellness Editor and Writer Read more